Regulatory mechanism of male fertility by seminal fluid
Project/Area Number |
15K07159
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Genetics/Chromosome dynamics
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Research Institution | Okayama University |
Principal Investigator |
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Research Collaborator |
KUBO Ayuko
MATSUKA Mirai
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Project Period (FY) |
2015-04-01 – 2018-03-31
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Project Status |
Completed (Fiscal Year 2017)
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Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
|
Keywords | ショウジョウバエ / 妊性 / 精液 / 栄養 / 細胞死 / 栄養シグナル / 転写制御因子 / タンパク質分解 |
Outline of Final Research Achievements |
The male reproductive organ accessory glands in Drosophila make components of seminal fluid. We examined the possibility that accessory gland cells function as a nutrient sensor when controlling reproductive ability (fecundity) in response to nutrient conditions. Of the main cells (~ 1,000) and the secondary cells (~ 60), we showed that the nutrient conditions during development change the number and size of secondary cells to optimize male fecundity. In addition, Dve and Abd-B were identified as factors that control gene expression in a nutrient-dependent manner.
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Report
(4 results)
Research Products
(9 results)
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[Journal Article] Nutrient conditions sensed by the reproductive organ during development optimize male fecundity in Drosophila2018
Author(s)
Kubo, A., Matsuka, M., Minami, R., Kimura, F., Sakata-Niitsu, R., Kokuryo, A., Taniguchi, K., Adachi-Yamada, T., and Nakagoshi, H.
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Journal Title
Genes to Cells
Volume: (印刷中)
Related Report
Peer Reviewed
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