Study on the mechanisms of photoperiodic time measurement regulating seasonal reproduction in vertebrates

• Project/Area Number: 15K07163
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Genetics/Chromosome dynamics
• Research Institution: National Institute for Basic Biology
• Principal Investigator: Otake Ai 基礎生物学研究所, 季節生物学研究部門, 特任助教 (60452067)
• Project Period (FY): 2015-10-21 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: 光周性 / 季節繁殖 / メダカ / 卵巣 / 地理的変異

Outline of Final Research Achievements

In seasonal reproduction, day length (photoperiod) is a cue to breed in the specific season for many animals, however, the molecular mechanisms of photoperiodic time measurement have not been clarified. Medaka, a small freshwater teleost, is a long-day breeder. We examined the response to changes of day lengths using various medaka populations collected from all over Japan, and found geographical variations in (1) a critical day length to induce reproduction and (2) response to short-day that induce reproductive quiescence. The present study aimed to identify the genes involved in the photoperiodic time measurement using these geographical variations. We conducted forward genetic approaches, and detected chromosomal regions involved in the response to day length.

Research Products

• [Journal Article] Seasonal changes in color perception (2018)
  • Author(s): Shimmura T, Nakayama T, Shinomiya A, Yoshimura T
  • Journal Title: General and Comparative Endcrinology Volume: 260 Pages: 171-174
  • DOI: 10.1016/j.ygcen.2017.12.010
  • Peer Reviewed
• [Journal Article] Dynamic plasticity in phototransduction regulates seasonal changes in color perception (2017)
  • Author(s): Shimmura Tsuyoshi、Nakayama Tomoya、Shinomiya Ai、Fukamachi Shoji、Yasugi Masaki、Watanabe Eiji、Shimo Takayuki、Senga Takumi、Nishimura Toshiya、Tanaka Minoru、Kamei Yasuhiro、Naruse Kiyoshi、Yoshimura Takashi
  • Journal Title: Nature Communications Volume: 8 Issue: 1 Pages: 412-412
  • DOI: 10.1038/s41467-017-00432-8
  • Peer Reviewed / Open Access
• [Presentation] メダカの地理的変異を利用した短日性繁殖停止機構の遺伝学的解析 (2017)
  • Author(s): 四宮愛、中務真愛、足立大輔、新村毅、永野惇、成瀬清、吉村崇
  • Organizer: 日本動物学会第88回大会
• [Presentation] Geographical variation and forward genetic approaches of photoperiodic time measurement in the teleost fish medaka (2016)
  • Author(s): Shinomiya A, Adachi D, Shimmura T, Nakatsukasa M, Nagano JA, Yasugi M, Naruse K, Yoshimura T
  • Organizer: The Joint meeting of the 22nd International Congress of Zoology (ICZ) / the 87th meeting of the ZSJ
  • Place of Presentation: Okinawa Institute of Science and Technology Graduate University (OIST)/Okinawa Convention Center (OCC), Kunigami/ Ginowan, Okinawa
  • Year and Date: 2016-11-14
  • Int'l Joint Research
• [Presentation] メダカの日長応答の地理的変異を利用した日長測時機構の遺伝学的解析 (2016)
  • Author(s): 四宮 愛、足立 大輔、新村 毅、中務 真愛、永野 惇、八杉 公基、成瀬 清、吉村 崇
  • Organizer: 弟23回日本時間生物学会学術大会
  • Place of Presentation: 名古屋大学豊田講堂、名古屋、愛知県
  • Year and Date: 2016-11-12
• [Presentation] Forward genetic analysis of photoperiodic time measurement in Medaka, Oryzias latipes (2016)
  • Author(s): Shinomiya A, Adachi D, Shimmura T, Nakatsukasa M, Nagano JA, Yasugi M, Naruse K, Yoshimura T
  • Organizer: The 64th NIBB Conference "Evolution of Seasonal Timers"
  • Place of Presentation: Okazaki Conference Center, Okazaki, Aichi
  • Year and Date: 2016-04-22
  • Int'l Joint Research
• [Presentation] Geographical variation in response to short-day in Medaka, Oryzias latipes (2016)
  • Author(s): Nakatsukasa M, Shinomiya A, Shimmura T, Adachi D, Nagano JA, Naruse K, Yoshimura T
  • Organizer: The 64th NIBB Conference "Evolution of Seasonal Timers"
  • Place of Presentation: Okazaki Conference Center, Okazaki, Aichi
  • Year and Date: 2016-04-22
  • Int'l Joint Research
• [Book] Seasonal regulation of reproduction in vertebrates: special focus on avian strategy. In: Reproductive and Developmental Strategies (2018)
  • Author(s): Shinomiya A, Yoshimura T
  • Total Pages: 20
  • Publisher: Springer Japan
• [Book] Reproductive and Developmental Strategies (2017)
  • Author(s): Shinomiya A, Yoshimura T
  • Publisher: Springer Japan
• [Book] Reproductive and Developmental Strategies (2016)
  • Author(s): Shinomiya, Yoshimura
  • Publisher: Springer Japan