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Studying aquatic adaptation of amniotes based on the comparative genomics of sea snakes

Research Project

Project/Area Number 15K07184
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Biodiversity/Systematics
Research InstitutionKyoto University

Principal Investigator

Kishida Takushi  京都大学, 野生動物研究センター, 特定助教 (40527892)

Co-Investigator(Renkei-kenkyūsha) TODA Mamoru  琉球大学, 熱帯生物圏研究センター, 准教授 (40378534)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywordsデノボアセンブル / 感覚受容体遺伝子 / 嗅覚 / AQP2 / ウミヘビ / ゲノムアセンブル / クロガシラウミヘビ / ヒロオウミヘビ / RNA-seq / 海洋環境適応進化 / ショットガンシークエンス
Outline of Final Research Achievements

In this study, whole-genomes of amphibious and fully aquatic sea snakes were sequenced and assembled, and compared with that of terrestrial snakes. As a result, it is suggested that many chemosensory receptor genes were lost from the genomes of sea snakes. In addition, expression of RNA sequences of remaining chemosensory receptor genes is not confirmed in the nasal cavity of fully aquatic sea snakes. Degeneration of the chemosensory receptor genes is also confirmed in the case of cetaceans, suggesting convergent evolution being caused by aquatic adaptation. However, unlike cetaceans, it is revealed that fully aquatic sea snakes can smell underwater. No fully aquatic amniotes are known to be able to smell underwater and sea snakes are the only exception from this rule.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (18 results)

All 2018 2017 2016 2015 Other

All Int'l Joint Research (3 results) Journal Article (3 results) (of which Peer Reviewed: 2 results,  Acknowledgement Compliant: 1 results) Presentation (10 results) (of which Int'l Joint Research: 3 results,  Invited: 2 results) Book (2 results)

  • [Int'l Joint Research] Northeast Ohio Medical University(米国)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] Northeast Ohio Medical University(米国)

    • Related Report
      2016 Research-status Report
  • [Int'l Joint Research] Northeast Ohio Medical University(米国)

    • Related Report
      2015 Research-status Report
  • [Journal Article] Evolution of the alternative AQP2 gene: Acquisition of a novel protein-coding sequence in dolphins2018

    • Author(s)
      Kishida Takushi、Suzuki Miwa、Takayama Asuka
    • Journal Title

      Molecular Phylogenetics and Evolution

      Volume: 118 Pages: 54-57

    • DOI

      10.1016/j.ympev.2017.09.012

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Population history of Antarctic and common minke whales inferred2017

    • Author(s)
      Takushi Kishida
    • Journal Title

      Marine Mammal Science

      Volume: 印刷中 Issue: 2 Pages: 645-652

    • DOI

      10.1111/mms.12369

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] 鯨類は海洋環境への適応進化の過程で嗅球の背側領域を失った2015

    • Author(s)
      岸田拓士
    • Journal Title

      Aroma Research

      Volume: 62 Pages: 37-39

    • NAID

      40020499300

    • Related Report
      2015 Research-status Report
  • [Presentation] ウミヘビ類から考える羊膜類の海洋環境適応と嗅覚の進化2017

    • Author(s)
      岸田拓士
    • Organizer
      第4回ケモビ研究会
    • Place of Presentation
      赤い風車(岩手県雫石町)
    • Year and Date
      2017-02-17
    • Related Report
      2016 Research-status Report
  • [Presentation] Olfactory Capability of Mysticetes Inferred from the Olfactory Receptor Repertoires and the Functional Regionalization of Olfactory Bulbs2017

    • Author(s)
      Kishida Takushi
    • Organizer
      22nd Biennial Conference on Marine Mammal Biology
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ウミヘビゲノムに探る羊膜類の海洋環境適応と嗅覚の進化2017

    • Author(s)
      岸田拓士, 工樂樹洋, 辰見香織, 戸田守
    • Organizer
      日本進化学会第19回大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 偶蹄類から鯨類へ:哺乳類の海洋環境適応に伴う生理的な変化、およびその背後にある遺伝子の進化2017

    • Author(s)
      岸田拓士
    • Organizer
      日本哺乳類学会2017年度大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Evolution of the loss of olfaction and olfactory bulbs in cetaceans2016

    • Author(s)
      Takushi Kishida, J. G. M. Thewissen
    • Organizer
      The 22nd international congress of zoology
    • Place of Presentation
      沖縄科学技術大学院大学(沖縄県恩納村)
    • Year and Date
      2016-11-14
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] 1個体全ゲノム配列に基づいたミンククジラの個体数変動推定と種分化2016

    • Author(s)
      岸田拓士
    • Organizer
      日本進化学会第18回大会
    • Place of Presentation
      東京工業大学(東京都目黒区)
    • Year and Date
      2016-08-25
    • Related Report
      2016 Research-status Report
  • [Presentation] Evolution and diversity of olfactory receptor genes among cetaceans, and the genetic basis of baleen whale olfaction2015

    • Author(s)
      Takushi Kishida
    • Organizer
      The 21st Biennial Conference on Marine Mammals
    • Place of Presentation
      サンフランシスコ(米国)
    • Year and Date
      2015-12-13
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] クロミンククジラのゲノムを解読しました2015

    • Author(s)
      岸田拓士
    • Organizer
      2015年度勇魚会シンポジウム
    • Place of Presentation
      日本大学藤沢キャンパス(神奈川県藤沢市)
    • Year and Date
      2015-11-28
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] Aquatic adaptation and the evolution of the sense of smell in whales2015

    • Author(s)
      岸田拓士
    • Organizer
      日本味と匂学会第49会大会
    • Place of Presentation
      十六プラザ(岐阜県岐阜市)
    • Year and Date
      2015-09-24
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 鯨類の嗅覚受容体遺伝子レパートリーの解析ーーヒゲクジラの嗅覚能力を分子から探る2015

    • Author(s)
      岸田拓士
    • Organizer
      日本進化学会第17回大会
    • Place of Presentation
      中央大学後楽園キャンパス(東京都文京区)
    • Year and Date
      2015-08-20
    • Related Report
      2015 Research-status Report
  • [Book] Brain evolution by design2017

    • Author(s)
      S. Shigeno, Y. Murakami, T. Nomura (編集)
    • Total Pages
      438
    • Publisher
      Springer Japan
    • Related Report
      2016 Research-status Report
  • [Book] クジラの鼻から進化を覗く2016

    • Author(s)
      岸田拓士
    • Total Pages
      123
    • Publisher
      慶応義塾大学出版会
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2022-06-06  

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