| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
|---|
| Outline of Final Research Achievements |
An aerobic anoxygenic photosynthetic bacterium Roseobacter denitrificans OCh114 requires two DNR-type transcriptional regulators, DNR1 and DNR2, for anaerobic growth by denitrification. Gene expression analyses using the mutant strains of some regulatory genes revealed that DNR1, DNR2, and the denitrifications genes constitute a cascade regulatory system. DNR1 regulates the expression of DNR2 and DNR2 directly regulates the expression of the denitrification genes in the system. An oxygen-responsive regulator FnrL was indirectly involved in the expression of the denitrification genes via regulation of the biosynthesis of heme, which is required for the activity of DNR. LOV-HK, which is involved in the regulation of the photosynthetic genes, was predicted to be involved in the light-responsive regulation of the denitrification genes in OCh114.
|
