| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Outline of Final Research Achievements |
Fermentation microbes such as yeast are exposed to extreme anaerobiosis during fermentation. Since mitochondria shrink in such environments, the role of mitochondria in the metabolism of yeast has not been studied in detail. However, this notion has hampered biosynthesis of complex substances that are related to mitochondrial metabolism.
In this study, we prepared respirative, fermentative and middle status yeasts, and studied their metabolome. From the metabolome data, we could construct a PLS regression equation to exactly predict the status of yeasts with high statistical significance. This knowledge will enable prediction of the respirative status of yeasts whose metabolomes were analyzed.
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