Reanalysis of the metabolome data by considering the mitochondrial status
| Project/Area Number |
15K07363
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Applied microbiology
|
|---|
| Research Institution | Saga University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2015-04-01 – 2018-03-31
|
| Project Status |
Completed (Fiscal Year 2017)
|
| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
|---|
| Keywords | メタボローム / 発酵 / 酵母 / ミトコンドリア / メタボローム解析 / 呼吸 / 酸化還元 / PLSDA / 統計解析 / 有用物質生産 |
|---|
| Outline of Final Research Achievements |
Fermentation microbes such as yeast are exposed to extreme anaerobiosis during fermentation. Since mitochondria shrink in such environments, the role of mitochondria in the metabolism of yeast has not been studied in detail. However, this notion has hampered biosynthesis of complex substances that are related to mitochondrial metabolism.
In this study, we prepared respirative, fermentative and middle status yeasts, and studied their metabolome. From the metabolome data, we could construct a PLS regression equation to exactly predict the status of yeasts with high statistical significance. This knowledge will enable prediction of the respirative status of yeasts whose metabolomes were analyzed.
|
Report
(3 results)
Research Products
(46 results)
-
-
-
-
-
[Journal Article] Chromosomal Aneuploidy Improves the Brewing Characteristics of Sake Yeast.2017
Author(s)
Kadowaki M, Fujimaru Y, Taguchi S, Ferdouse J, Sawada K, Kimura Y, Terasawa Y, Agrimi G, Anai T, Noguchi H, Toyoda A, Fujiyama A, Akao T, Kitagaki H.
-
Journal Title
Applied and Environmental Microbiology
Volume: 83
Issue: 24
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
-
-
-
-
-
-
-
-
-
[Journal Article] Chemical analysis of the sugar moiety of monohexosylceramide contained in koji, Japanese traditional rice fermented with Aspergillus.2016
Author(s)
Hiroshi Hamajima, Ayumi Fujikawa, Mikako Yamashiro, Takatoshi Ogami, Seiichi Kitamura, Masahito Tsubata, Sei Tan, Haruka Matsunaga, Kazutaka Sawada, Satoshi Kumagai, Nobuyuki Hayashi, Koji Nagao, Teruyoshi Yanagita, Takuji Oka, Susumu Mitsutake and Hiroshi Kitagaki*
-
Journal Title
Fermentation
Volume: 2
Issue: 1
Pages: 2-2
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
-
-
-
-
[Journal Article] Glucosylceramide contained in Koji mold-cultured cereal confers membrane and flavor modification and stress tolerance to Saccharomyces cerevisiae during coculture fermentation.2015
Author(s)
Kazutaka Sawada, Tomoya Sato, Hiroshi Hamajima, Lahiru Niroshan Jayakody, Miyo Hirata, Mikako Yamashiro, Marie Tajima, Susumu Mitsutake, Koji Nagao, Keisuke Tsuge, Fumiyoshi Abe, Kentaro Hanada, and Hiroshi Kitagaki*
-
Journal Title
Applied and Environmental Microbiology, 81(11):3688-98.
Volume: 81
Issue: 11
Pages: 3688-3698
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
-
-
-
-
-
-
-
-
-
-
-
[Presentation] 清酒酵母の 1 倍体取得方法の最適化2015
Author(s)
澤田 和敬, 田口 誠我, 福崎 久詩 , 門脇 真史, 藤丸 裕貴, 鶴田 裕美, 吉村 臣史, 北垣 浩志
Organizer
日本生物工学会
Place of Presentation
城山観光ホテル
Year and Date
2015-10-26
Related Report
-
-
-
[Presentation] 麹グルコシルセラミドは酵母に発酵能・醸造形質を賦与する2015
Author(s)
佐藤 友哉, 澤田 和敬, 浜島 弘史, ジャヤコディ ラヒル 平田 みよ, 山城 美香子, 田島 麻理恵, 光武 進, 永尾 晃治, 柘植 圭介, 阿部 文快, 花田 賢太郎, 北垣 浩志
Organizer
日本生物工学会
Place of Presentation
城山観光ホテル
Year and Date
2015-10-26
Related Report
-
-
-
-
-
[Presentation] 蜂の子に含まれる脂質の抗炎症作2015
Author(s)
酒谷 真以, 濱 侑希, 松永 陽香 , 門脇 真史, 鶴田 裕美, 柘植 圭介, 吉賀 豊司, 浜島 弘史, 北垣 浩志
Organizer
日本生物工学会
Place of Presentation
城山観光ホテル
Year and Date
2015-10-26
Related Report
-
[Book] こうじ菌2018
Author(s)
北垣浩志
Total Pages
32
Publisher
農文協
ISBN
9784540171765
Related Report
-
-
-
-
-
-
-
-
