A cross talk between immuno-related genes and hormon-related genes
| Project/Area Number |
15K07555
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Aquatic bioproduction science
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| Research Institution | University of Miyazaki |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
酒井 正博 宮崎大学, 農学部, 教授 (20178536)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | クルマエビ / 生体防御因子 / ホルモン / ＷＳＳＶ / ウイルス / 細菌 / サイトカイン / インスリン様ホルモン / 低酸素 |
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| Outline of Final Research Achievements |
In shrimp aquaculture, high-stocking farming with phytoplankton blooming decreases the dissolved oxygen concentrations in the pond water. Exposure of shrimp to hypoxia induces the molting and molted shrimp are susceptible to infection due to its physical and physiological weakness, e.g. soft shell and loss of energy.
Hypoxia-inducible factor (HIF) is a transcriptional factor in the basic helix-loop-helix/PAS family and is activated in response to hypoxic stress. However, information of HIF and other related factors of the HIF pathway in crustaceans are not well known. In this study, we cloned MjHIF-1α, an inhibitory factor, MjFIH-1, and MjVHL from kuruma shrimp (Marsupenaeus japonicus). MjVHL is the first crustacean VHL ortholog cloned in this study. MjHIF-1α and MjVHL were highly expressed in the intestine. MjHIF-1α expression in the hypoxic group increased significantly 24 h after the hypoxia exposure and expression of MjVHL decreased significantly 6 h after hypoxia stimulation.
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Report
(4 results)
Research Products
(36 results)
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[Journal Article] Enhancement of immune response and resistance against Vibrio parahaemolyticus in kuruma shrimp (Marsupenaeus japonicus) by dietary supplementation of β-1,4-mannobiose2017
Author(s)
Gehad E Elshopakey, Engy F Risha, Osama A.M Abdalla, Yo Okamura, Vuduc Hanh, Masahisa Ibuki, Raja Sudhakaran, Toshiaki Itami,
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Journal Title
Fish and Shellfish Immunology,
Volume: 74
Pages: 26-34
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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[Journal Article] Antiviral activity of 3-(1-chloropiperidin-4-yl)-6-fluoro benzisoxazole 2 against White spot syndrome virus in Freshwater crab, Paratelphusa hydrodomous.2016
Author(s)
Rajashekar Reddy, C.B., Dinesh, S., Anusha, N., Itami, T., Rajasekhara Reddy, S., Sudhakaran,
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Journal Title
Aquaculture Research
Volume: -
Issue: 8
Pages: 2677-2681
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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[Presentation] Enhancement of Immune Responses and Resistance to Vibrio parahaemolyticus in Kuruma Shrimp (Marsupenaeus japonicus) by Dietary Supplementation of β-1, 4-Mannobiose,2017
Author(s)
Gehad E. Elshopakey, Engy F. Risha, Osama A. Abdalla, Yo Okamura, Vu Duc Hanh, Masahisa Ibuki and Toshiaki Itami,
Organizer
The 13th International Conference “ASIAN Community Knowledge Networks for the Economy, Society, Culture, and Environmental Stability”
Related Report
Int'l Joint Research
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