| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Outline of Final Research Achievements |
Artificial sex control with hormonal manipulation is an effective tool for aquaculture production of commercially valuable monosex fish, while functionally complete sex change requires optimized administration with proper dose and period. To investigate the cause of functional deficiency in sex change for practical use, histogenetic and organogenetic process of gonadal formation was examined in relation to the failure of artificial masculinization of carp and salmon. In salmon, an epithelial cell population was observed in the first step of sperm duct formation in genetic male, while this histogenesis was frequently deficient in androgen treated (masculinized) genetic female. In carp, many of genetic female treated with the hormonal manipulation had testes, but milt could not be stripped in many of them, suggesting some physiological disorder.
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