| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Outline of Final Research Achievements |
In this study, we examined the neural mechanisms underlying the regulation of aggressive and submissive behaviors by neuropeptide hormone (arginine vasotocin; AVT) in male medaka fish. We demonstrated that the neurons with high expression of AVT mainly send their fibers into the distinct brain regions between the aggressive (dominant) male and the submissive (subordinate) male after their competition. The different subtypes of AVT-receptors (AVT-R) was shown at a high level in each brain region of the dominants and the subordinates. In addition, we conducted a preliminary contest between two males of the AVT-R gene knock-out medaka. These males have similar high aggression throughout the contest.
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