Treatment of mastitis using temporal cessation of milking
| Project/Area Number |
15K07692
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Animal production science
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| Research Institution | Hiroshima University |
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Principal Investigator |
Isobe Naoki 広島大学, 生物圏科学研究科, 准教授 (80284230)
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| Co-Investigator(Renkei-kenkyūsha) |
OKITA MIKI 広島大学, 大学院生物圏科学研究科, 助教 (30611842)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 乳房炎 / エストラジオール / 抗菌因子 / ショート乾乳 / 乳量 / エストロゲン / 水チャネル |
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| Outline of Final Research Achievements |
The aim was to explore the effect of estrogen and temporal cessation of milking for 3 days on mammary immune function in order to develop new mastitis treatment system. Estrogen injection or temporal cessation of milking reduced milk yield and increased antimicrobial components concentration in milk. Combination of E treatment and temporal cessation of milking upregulated antimicrobial components in milk dramatically compared with that only temporal cessation of milking. These results suggest that temporal cessation of milking together with E augmented innate immune function which can be utilized to the treatment of mastitis.
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Report
(4 results)
Research Products
(52 results)
