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Development of selection method for desired change using information on SNP and verification of improving efficiency in swine

Research Project

Project/Area Number 15K07701
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Animal production science
Research InstitutionTohoku University

Principal Investigator

Satoh Masahiro  東北大学, 農学研究科, 教授 (70370658)

Project Period (FY) 2015-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2018: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Keywords制限付き選抜法 / コンピュータシミュレーション / 分割行列 / 制限付き選抜 / ゲノム関係行列
Outline of Final Research Achievements

In this study, we first examined the efficient operation method and algorithm for generating efficient inverse matrix for calculating inversion of genome relationship matrix using SNP information, such as improvement of various arithmetic algorithms. As a result of applying the Gaussian elimination method to the division method, it became clear that although the operation time differs depending on the rank of the matrix, there is a matrix size that can be calculated most efficiently. Furthermore, as a result of examining in detail the calculation method of the inverse matrix by the division method, it became clear that it is effective in the case of a dense matrix where the symmetric matrix and the original matrix do not fit in the memory. Since these characteristics apply to the genome relation matrix, the program to calculate the inverse matrix using the division method was effective.

Academic Significance and Societal Importance of the Research Achievements

わが国における豚の系統造成では改良目標を設定した選抜法が多く行われ、最近では豚の一部地域内において遺伝的能力評価が行われるとともに、全国評価に向けた取り組みがなされている。また、研究レベルでは豚においてSNP情報を利用した改良の可能性が示唆されており、この情報を遺伝的能力評価に利用するための適切な演算法を明らかにしたもので、SNP情報を用いた場合の効率的な種豚評価が期待される。

Report

(4 results)
  • 2018 Final Research Report ( PDF )
  • 2017 Annual Research Report
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (6 results)

All 2018 2017 2016 2015

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (4 results) (of which Int'l Joint Research: 2 results)

  • [Journal Article] An alternative derivation method of mixed model equations from best linear unbiased prediction (BLUP) and restricted BLUP of breeding values not using maximum likelihood2018

    • Author(s)
      M. Satoh
    • Journal Title

      Animal Science Journal

      Volume: 89 Issue: 6 Pages: 876-879

    • DOI

      10.1111/asj.13016

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 豚の系統造成において相対希望改良量を達成するための育種価に対する重み付け値を得るための血縁情報量2015

    • Author(s)
      佐藤正寛
    • Journal Title

      日本養豚学会誌

      Volume: 52 Pages: 43-49

    • NAID

      130005101695

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] An alternative derivation method of mixed model equations not using maximum likelihood2018

    • Author(s)
      M. Satoh
    • Organizer
      The 11st World Congress on Genetics Applied to Livestock Production
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 育種価の推定精度について2017

    • Author(s)
      佐藤正寛
    • Organizer
      第14回統計遺伝育種研究会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Genetic evaluation for selection with constraints and its geometrical interpretation2016

    • Author(s)
      Satoh, M., Ishii, K.
    • Organizer
      17th Asian-Australasian Association of Animal Production Societies Animal Science Congress
    • Place of Presentation
      九州産業大学(福岡県福岡市)
    • Year and Date
      2016-08-22
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] インプリンティングを考慮したゲノミックBLUP法における推定性能の検証2015

    • Author(s)
      西尾元秀・佐藤正寛
    • Organizer
      日本畜産学会第120回大会
    • Place of Presentation
      酪農学園大学(北海道江別市)
    • Year and Date
      2015-09-10
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2020-03-30  

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