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Observation of cerebrospinal fluid movement using TimeSLIP in small animal

Research Project

Project/Area Number 15K07753
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Veterinary medical science
Research InstitutionNihon University

Principal Investigator

KITAGAWA Masato  日本大学, 生物資源科学部, 教授 (50409067)

Co-Investigator(Kenkyū-buntansha) 杉谷 博士  日本大学, 生物資源科学部, 教授 (20050114)
Research Collaborator YAMADA Shinya  
ITO Daisuke  
ISHIKAWA Chieko  
ONO Kaori  
TANAKA Natsumi  
OTA Shigeo  
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords脳脊髄液 / Time-SLIP / 脊髄空洞症 / 水頭症 / 脳脊髄液循環 / Time-SLP / Time-SLIP法
Outline of Final Research Achievements

Cases with neurological signs, that came our hospital, were taken Time-spatial labeling inversion pulse (Time-SLIP). Hydrocephalus or syringomyelia as case with abnormal cerebrospinal fluid (CSF) circulation and idiopathic epilepsy as control group were selected and investigated. In syringomyelia cases, there were differences in appearance probability of CSF movement at the cervical area, comparing to other disease. It was suggested that changes of CSF circulation at the cervical area contributes to syringomyelia. A syringomyelia case, which movement to syrinx did not appear, was treated with a ventriculoperitoneal shunt, and syrinx resolved. It was suggested that change in CSF circulation might resolve syringomyelia.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (12 results)

All 2017 2016 2015

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (11 results) (of which Int'l Joint Research: 2 results,  Invited: 2 results)

  • [Journal Article] Comparison of conventional magnetic resonance imaging and nonenhanced three dimensional time-of-flight magnetic resonance angiography findings between dogs with meningioma and dogs with intracranial histiocytic sarcoma: 19 cases (2010–2014)2016

    • Author(s)
      Chieko Ishikawa, Daisuke Ito, Masato Kitagawa, Toshihiro Watari
    • Journal Title

      Journal of American Veterinary Association

      Volume: 印刷中

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Presentation] time spatial labeling inversion pulse( Time-SLIP)法を用いた先天性水頭症犬 3頭における脳脊髄液循環動態の検討2017

    • Author(s)
      田中那津美、伊藤大介、石川智恵子、北川勝人
    • Organizer
      日本獣医師会獣医学術学会年次大会
    • Place of Presentation
      県立音楽堂、金沢市アートホール、ホテル金沢、ホテル日航、金沢市(石川県)
    • Year and Date
      2017-02-24
    • Related Report
      2016 Research-status Report
  • [Presentation] 犬の脳脊髄液循環障害 ー病態・診断そして治療までー2017

    • Author(s)
      北川勝人
    • Organizer
      内科学アカデミー
    • Place of Presentation
      パシフィコ横浜、横浜市(神奈川県)
    • Year and Date
      2017-02-17
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] 犬の脳脊髄液循環障害-病態・診断そして治療まで2017

    • Author(s)
      北川勝人
    • Organizer
      日本獣医内科学アカデミー学術大会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 先天性水頭症3頭における脳脊髄液循環動態の検討2017

    • Author(s)
      田中那津美、伊藤大介、石川智恵子、北川勝人
    • Organizer
      日本獣医師会獣医学術学会年次大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] CEREBROSPINAL FLUID MOVEMENT USING MAGNETIC RESONACE SPIN LABELING IN 3 DOGS WITH CONGENITAL HYDROCEPHALUS.2016

    • Author(s)
      N. Tanaka1,, D. Ito, C. Ishikawa , S. Ohta, M. Kitagawa
    • Organizer
      European College of Veterinary Neurology
    • Place of Presentation
      The university of Edinburgh, Edinburgh ( Scotland)
    • Year and Date
      2016-09-15
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Visualization of intracranial vessels in toy-breed dogs using three dimensional time-of-flight magnetic resonance angiography.2016

    • Author(s)
      C. Ishikawa, D. Ito, N. Tanaka, S. Ohta, M. Kitagawa
    • Organizer
      European College of Veterinary Neurology
    • Place of Presentation
      The university of Edinburgh, Edinburgh ( Scotland)
    • Year and Date
      2016-09-15
    • Related Report
      2016 Research-status Report
  • [Presentation] 脳腫瘍摘出術を行った犬45症例の回顧的研究2016

    • Author(s)
      北川勝人、伊藤大介、田中那津美、太田茂雄、石川智恵子
    • Organizer
      獣医神経病学会
    • Place of Presentation
      奈良春日野国際フォーラム甍~I・RA・KA~ , 奈良市(奈良県)
    • Year and Date
      2016-07-16
    • Related Report
      2016 Research-status Report
  • [Presentation] 水頭症の犬のMRI所見2016

    • Author(s)
      田中那津美、伊藤大介、石川智恵子、小野かおり、北川勝人
    • Organizer
      平成27年度獣医学術学会年次大会
    • Place of Presentation
      秋田キャッスルホテル(秋田県・秋田市)
    • Year and Date
      2016-02-27
    • Related Report
      2015 Research-status Report
  • [Presentation] 脳実質内に発生した化膿性肉芽腫性炎症と診断された腫瘤を摘出した猫の1 例2015

    • Author(s)
      田中那津美,伊藤大介,賀川由美子,北川勝人
    • Organizer
      第91回獣医麻酔外科学会
    • Place of Presentation
      札幌コンベンションセンター(北海道・札幌市)
    • Year and Date
      2015-12-19
    • Related Report
      2015 Research-status Report
  • [Presentation] MRI FINDINGS AND ICP OF DOG WITH HYDROCEPHALUS2015

    • Author(s)
      N.Tanaka, D.Ito, C. Ishikawa, S. Ohta, M. Kitagawa
    • Organizer
      European College of Veterinary Neurology
    • Place of Presentation
      Amsterdam(Netherlands)
    • Year and Date
      2015-09-18
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 獣医学領域における脳腫瘍外科の現状2015

    • Author(s)
      北川勝人
    • Organizer
      第90回獣医麻酔外科学会
    • Place of Presentation
      大宮ソニックシティ(埼玉県・さいたま市)
    • Year and Date
      2015-06-20
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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