Observation of cerebrospinal fluid movement using TimeSLIP in small animal
| Project/Area Number |
15K07753
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Veterinary medical science
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| Research Institution | Nihon University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
杉谷 博士 日本大学, 生物資源科学部, 教授 (20050114)
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| Research Collaborator |
YAMADA Shinya
ITO Daisuke
ISHIKAWA Chieko
ONO Kaori
TANAKA Natsumi
OTA Shigeo
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 脳脊髄液 / Time-SLIP / 脊髄空洞症 / 水頭症 / 脳脊髄液循環 / Time-SLP / Time-SLIP法 |
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| Outline of Final Research Achievements |
Cases with neurological signs, that came our hospital, were taken Time-spatial labeling inversion pulse (Time-SLIP). Hydrocephalus or syringomyelia as case with abnormal cerebrospinal fluid (CSF) circulation and idiopathic epilepsy as control group were selected and investigated. In syringomyelia cases, there were differences in appearance probability of CSF movement at the cervical area, comparing to other disease. It was suggested that changes of CSF circulation at the cervical area contributes to syringomyelia. A syringomyelia case, which movement to syrinx did not appear, was treated with a ventriculoperitoneal shunt, and syrinx resolved. It was suggested that change in CSF circulation might resolve syringomyelia.
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Report
(4 results)
Research Products
(12 results)
