| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Outline of Final Research Achievements |
1,4-Zwitterionic intermediates which were generated by activation of 3-ethoxycyclobutanones with an appropriate Lewis acid reacted with azobenzenes, quinolines, isoquinolines, ynamides, nitrosobenzenes, and reactive alkynes gave the corresponding 6-membered cyclic compounds by formal [4+2] cycloaddition reactions. A zwitterionic intermediate generated from 3-phenylcyclobutanones reacted aromatics to afford Friedel-Crafts adducts. Also, an adduct between 1,4-ketoaldehyde and tosylhydrazine rected with nucleophiles under activation with a Lewis acid to give dihydropyridazines.
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