Synthesis and Reaction of N-Allenylimides
Project/Area Number |
15K07881
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Chemical pharmacy
|
Research Institution | Hiroshima International University |
Principal Investigator |
Sueda Takuya 広島国際大学, 薬学部, 准教授 (40260682)
|
Co-Investigator(Kenkyū-buntansha) |
柳田 玲子 広島国際大学, 薬学部, 教授 (80239821)
|
Project Period (FY) |
2015-04-01 – 2018-03-31
|
Project Status |
Completed (Fiscal Year 2017)
|
Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
Keywords | N-アレニルイミド / アレニミド / ヘテロ環合成 / N-アルキニルイミド / イニミド / アレナミド / イナミド / 複素環 / ヘテロ環化合物 / ヘテロ環 |
Outline of Final Research Achievements |
Among the heteroatom-substituted alkynes and allenes, those with nitrogen substitutions have become an important building block in modern organic synthesis. In contrast to the well-defined ynamides and allenamides, to date, there are little examples of imide derivatives. We have recently reported the Cu-catalyzed coupling of alkynyl(triaryl)bismuthonium salts with imides to furnish the first reliable synthetic method of ynimides. Now we found a first convenient approach for the synthesis of internal allenimides via silver-mediated isomerization of ynimides. Allenimides could be used as synthetic building units in the synthesis of heterocyclic compounds.
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Report
(4 results)
Research Products
(19 results)