| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Outline of Final Research Achievements |
Organofluorine compounds have considerable much attention in the field of medicinal and agricultural chemistry from the view of point of their unique characteristics such as thermal and chemical stability, surface tension lowering ability, hydrophobicity and lipophobicity. We are engaged in developing partially fluorinated phospholipid membranes as membrane protein reconstitution matrices toward ultra-thin film typed biosensors. As an extension of these researches, we prepared new fluorinated fluorescent probes, and found that the lateral diffusivity in the fluorinated phospholipids bilayers observed with the probes was enough to exhibit suitable fluidity for membrane protein reconstitutions.
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