| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Outline of Final Research Achievements |
The aim of the present research is the development of an early detection method for Chronic Obstructive Pulmonary Disease (COPD). For this purpose, the peptide sequence-specific fluorescence derivatization reaction has been utilized in order to detect the proline-glycine-proline tripeptide which is known as a biomarker for COPD. The sputum sample from a COPD patient was applied to the fluorescence reaction, and the resulting supernatant was analyzed with high-performance liquid chromatography. As the result, a minimal amount of the target marker was successfully quantified.
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