| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
To develop the drug for alveolar regeneration based on inducing differentiation of alveolar progenitor cells, we aimed to find efficient delivery system of the drug to the site of action. Using the drug carrier ssPalm, the drug for alveolar regeneration showed alveolar repairing effect efficiently. The suitable particle size, enclosed capacity, and the minimum dose of drug were determined. Furthermore, ssPalm, which repaired collapsed alveoli, showed rapidly escaping from an endosome in a cell and we showed the possibility of making inhalations for clinical application.
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