| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
|---|
| Outline of Final Research Achievements |
Bio-orgaometallics is a research strategy in which organic-inorganic hybrid molecules are used as a tool to analyze biological systems. Based on this strategy, we got hybrid molecules (1,10-phenanthroline with or without zinc or rhodium) from a library of organic-inorganic hybrid molecules. It was found that the expression of syndecan-4, a small heparan sulfate proteoglycan, is induced via the hypoxia-inducible factor-1α/β pathway when prolyl hydroxylase domain-containing protein 2 is inhibited.
|
