Establishment of the social evaluation by the saliva oxytocin measurement
| Project/Area Number |
15K08093
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Medical pharmacy
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| Research Institution | University of Fukui |
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Principal Investigator |
Kosaka Hirotaka 福井大学, 子どものこころの発達研究センター, 教授 (70401966)
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| Co-Investigator(Kenkyū-buntansha) |
齋藤 大輔 金沢大学, 子どものこころの発達研究センター, 特任准教授 (30390701)
藤澤 隆史 福井大学, 子どものこころの発達研究センター, 特命講師 (90434894)
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| Co-Investigator(Renkei-kenkyūsha) |
TOMODA Akemi 福井大学, 子どものこころの発達研究センター, 教授 (80244135)
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| Research Collaborator |
FUJIOKA Toru
OKAMOTO Yuko
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | オキシトシン / 社会性 / 唾液濃度 |
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| Outline of Final Research Achievements |
Although there are some reports measures the peripheral oxytocin levels, the most samples are invasive plasma sample. This way is too difficult for children and individuals with autism spectrum disorders which have hyperesthesia to get blood sampling. The aim of this study is to evaluate saliva oxytocin level as the easily measurement for sociality. We conducted the difference peripheral oxytocin level in plasma and saliva samples using conventional ELISA methods. In addition, we conducted a correlation analysis to investigate relationships between saliva oxytocin levels and percentage fixation time allocated to sociality movies.
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Report
(4 results)
Research Products
(13 results)
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[Journal Article] Age-dependent abnormalities in body- and face-sensitive activation of the EBA and FFA in individuals with ASD2017
Author(s)
Okamoto Y, Kosaka H, Kitada R, Seki A, Tanabe HC, Hayashi MJ, Kochiyama T, Saito DN, Yanaka HT, Munesue T, Ishitobi M, Omori M, Wada Y, Okazawa H, Koeda T, Sadato N
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Journal Title
Neuroscience Research
Volume: 印刷中
Pages: 30243-30247
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
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[Journal Article] Gazefinder as a clinical supplementary tool for discriminating between autism spectrum disorder and typical development in male adolescents and adults.2016
Author(s)
Fujioka T, Inohara K, Okamoto Y, Masuya Y, Ishitobi M, Saito DN, Jung M, Arai S, Matsumura Y, Fujisawa TX, Narita K, Suzuki K, Tsuchiya JK, Mori N, Katayama T, Sato M, Munesue T, Okazawa H, Tomoda A, Wada Y, Kosaka H.
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Journal Title
Molecular Autism
Volume: 7
Issue: 1
Pages: 19-19
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Oxytocin efficacy is modulated by dosage and oxytocin receptor genotype in young adults with high-functioning autism: a 24-week randomized clinical trial.2016
Author(s)
Kosaka H, Okamoto Y, Munesue T, Yamasue H, Inohara K, Fujioka T, Anme T, Orisaka M, Ishitobi M, Jung M, Fujisawa TX, Tanaka S, Arai S, Asano M, Saito DN, Sadato N, Tomoda A, Omori M, Sato M, Okazawa H, Higashida H, Wada Y.
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Journal Title
Translational Psychiatry
Volume: 6
Issue: 8
Pages: e872-e872
DOI
NAID
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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