| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
Riboflavin (Vitamin B2) is a orange-yellow water-soluble vitamin, which plays important roles in the metabolism of glucose, amino acids and lipids. In the present study, we analyzed the pathology of the disruption in riboflavin transporter RFVT gene. It was revealed that the disruption of RFVT gene induced metabolic disorders, caused by riboflavin deficiency, in mice. These results will contribute to the development of therapy in RFVT-genetic rare diseases.
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