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Morphological study of the vagus nerve and pelvic nerve plexus branches of the parasympathetic nervous distributed in the colon

Research Project

Project/Area Number 15K08143
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field General anatomy (including histology/embryology)
Research InstitutionIwate Medical University

Principal Investigator

YAN JUN  岩手医科大学, 医学部, 准教授 (20316350)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Keywords自律神経 / 上下腹神経叢 / 下下腹神経叢 / 逆行性標識 / ヒト / ラット / Flk1マウス / 内臓神経線維 / 結腸 / 骨盤神経叢 / 腸内神経叢 / 順行性標識
Outline of Final Research Achievements

Visceral nerve fibers distributed in the human colon is still unclear. There was no difference in "distribution pattern" of the superior hypogastric plexus distributed in the colon of humans and rats. Labeling the superior hypogastric plexus of the rat suggested that the peripheral distribution in the colon is very extensively. Since neurons of these visceral nerve fibers were not observed in the sacral part of spinal cord, but were observed only in the lumbar sympathetic ganglia, it seems that the characteristic of this plexus fiber of rat is only "sympathetic nerve fiber". The parasympathetic fibers derived from the pelvis distributed in the colon are presumed to be components of the "inferior hypogastric plexus". The parasympathetic nerve fiber component distributed in the midgut was observed with transgenic mouse Flk1 early embryo, and the VIP staining method was also established.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (8 results)

All 2017 2015

All Journal Article (6 results) (of which Peer Reviewed: 6 results,  Open Access: 5 results,  Acknowledgement Compliant: 1 results) Presentation (2 results) (of which Invited: 1 results)

  • [Journal Article] Reinvestigation of the Morphological Characteristics of the Lateral Ulnar Collateral Ligament in Humans2017

    • Author(s)
      Karen Tokunaga, Kotaro Sato, Goro Tajima, Jun Yan, Yoshikuni Mimata, Katsumi Tajima, Yuki Kikuchi, Minoru Doita
    • Journal Title

      Okajimas Folia Anatomica Japonica

      Volume: 93 Pages: 45-48

    • NAID

      130007313348

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] The right-sided aortic arch with unusual course of bilateral recurrent laryngeal nerves: a report of rare variations2017

    • Author(s)
      Jun Yan, Jun Kanazawa, Norio Numata, Jiro Hitomi
    • Journal Title

      Surg Radiol Anat

      Volume: 39 Issue: 2 Pages: 223-228

    • DOI

      10.1007/s00276-016-1717-7

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Origin of the Celiac and Superior Mesenteric Arteries in a Common Trunk – Description of a Rare Vessel Variation of the Celiacomesenteric Trunk with a Literature Review2015

    • Author(s)
      Jun Yan, Yoshie Nagasawa, Masato Nakano, Jiro Hitomi
    • Journal Title

      Okajimas Folia Anatomica Japonica

      Volume: 91 Pages: 45-48

    • NAID

      130004705808

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Clarification of the distribution pattern of the twig(s) of radial nerve innervating brachial muscle in human2015

    • Author(s)
      Jun Yan, Kazuki Masu, Karen Tokunaga, Yoshie Nagasawa, Jiro Hitomi
    • Journal Title

      Austin J Musculoskeletal Disorders

      Volume: 2 Pages: 1014-1016

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Multiple arteries supplying the human liver: A case report of a rare variation of the blood supplying pattern in a Japanese population2015

    • Author(s)
      Jun Yan, Karen Tokunaga, Hirotaka Takahashi, Jiro Hitomi
    • Journal Title

      Edorium J Anatomy and Embryology

      Volume: 2 Pages: 1-5

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Difficult points in current gross anatomy education and research2015

    • Author(s)
      Jun Yan
    • Journal Title

      Edorium J Anatomy and Embryology

      Volume: 2 Pages: 18-19

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 動脈弓より直接起始する左椎骨動脈の破格2017

    • Author(s)
      金澤潤、燕 軍、木村英二、人見次郎
    • Organizer
      日本解剖学会
    • Place of Presentation
      長崎市
    • Year and Date
      2017-03-26
    • Related Report
      2016 Research-status Report
  • [Presentation] 脊髄前角の運動ニューロンの配列と末梢神経の分布2017

    • Author(s)
      燕 軍
    • Organizer
      岩手医学会
    • Related Report
      2017 Annual Research Report
    • Invited

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Published: 2015-04-16   Modified: 2019-03-29  

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