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Development of termination of resuscitation rule for out-of-hospital cardiac arrest

Research Project

Project/Area Number 15K08543
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical sociology
Research InstitutionKanazawa University

Principal Investigator

Goto Yoshikazu  金沢大学, 医学系, 准教授 (60282167)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords院外心停止 / 心肺蘇生 / 蘇生中止 / 病院前救護 / 地域医療学 / 心停止 / 医療系社会学 / 地域医療 / 医療社会学
Outline of Final Research Achievements

Using Japanese nationwide registry for out-of-hospital cardiac arrest (OHCA), we have developed a termination-of-resuscitation (TOR) rule in the field for patients with refractory OHCA, including the resuscitation duration by emergency medical services (EMS) personnel. The developed TOR rule is as follows: EMS personnel could consider termination of resuscitation in the field if patients meet all 3 of following criteria; (1) unwitnessed arrest (2)initial non-shockable rhythm, and (3) no return of spontaneous circulation after 15 minutes of EMS-initiated cardiopulmonary resuscitation. The specificity and positive predictive value for predicting 1-month death in patients who met these 3 criteria were 99.1% and 98.8%, respectively. Implementation of this TOR rule would have reduced the percentage of patients transported to the emergency department, approximately 9%, and the number of attendant hazards to EMS personnel, and have improved the utilization of hospital healthcare resources.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (28 results)

All 2018 2017 2016 2015 Other

All Journal Article (9 results) (of which Peer Reviewed: 9 results,  Open Access: 8 results,  Acknowledgement Compliant: 1 results) Presentation (17 results) (of which Int'l Joint Research: 11 results) Remarks (2 results)

  • [Journal Article] Timing and sequence of advanced airway interventions in out-of-hospital cardiac arrest.2018

    • Author(s)
      Goto Y
    • Journal Title

      J Public Health Emerg

      Volume: 2 Pages: 6-6

    • DOI

      10.21037/jphe.2018.02.04

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Conventional versus chest-compression-only cardiopulmonary resuscitation by bystanders for children with out-of-hospital cardiac arrest2018

    • Author(s)
      Goto Yoshikazu、Funada Akira、Goto Yumiko
    • Journal Title

      Resuscitation

      Volume: 122 Pages: 126-134

    • DOI

      10.1016/j.resuscitation.2017.10.015

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Reply to: Over time, differences in survival and favorable neurologic outcomes between conventional and compression-only cardiopulmonary resuscitation have been gradually reduced in pediatric out-of-hospital cardiac arrest2018

    • Author(s)
      Goto Yoshikazu、Funada Akira、Goto Yumiko
    • Journal Title

      Resuscitation

      Volume: 124 Pages: e9-e10

    • DOI

      10.1016/j.resuscitation.2017.12.023

    • NAID

      120006452367

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Relationship between emergency medical services response time and bystander intervention in patients with out-of-hospital cardiac arrest.2018

    • Author(s)
      Goto Y, Funada A, Goto Y
    • Journal Title

      J Am Heart Assoc

      Volume: 7 Issue: 9

    • DOI

      10.1161/jaha.117.007568

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Bystander interventions for out-of-hospital cardiac arrests: substantiated critical components of the chain of survival.2017

    • Author(s)
      Goto Y
    • Journal Title

      J Emerg Crit Care Med

      Volume: 1 Issue: 7 Pages: 12-12

    • DOI

      10.21037/jeccm.2017.06.01

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Subsequent shockable rhythm during out-of-hospital cardiac arrest in children with initial non-shockable rhythms: a nationwide population-based observational study.2016

    • Author(s)
      Goto Y, Funada A, Goto Y.
    • Journal Title

      Am Heart Assoc

      Volume: 5 Issue: 10

    • DOI

      10.1161/jaha.116.003589

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Duration of prehospital cardiopulmonary resuscitation and favorable neurological outcomes for pediatric out-of-hospital cardiac arrests: A nationwide, population-based cohort study.2016

    • Author(s)
      Goto Y, Funada A, Goto Y.
    • Journal Title

      Circulation

      Volume: 134 Issue: 25 Pages: 2046-2059

    • DOI

      10.1161/circulationaha.116.023821

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Between the Duration of Cardiopulmonary Resuscitation and Favorable Neurological Outcomes After Out-of-Hospital Cardiac Arrest: A Prospective, Nationwide, Population-Based Cohort Study.2016

    • Author(s)
      Yoshikazu Goto, Akira Funada, Yumiko Goto
    • Journal Title

      J Am Heart Assoc

      Volume: 5 Issue: 3

    • DOI

      10.1161/jaha.115.002819

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Neurological outcomes in children dead on hospital arrival.2015

    • Author(s)
      Yoshikazu Goto, Akira Funada, Yumiko Nakatsu-Goto
    • Journal Title

      Critical Care

      Volume: 19 Issue: 1 Pages: 410-410

    • DOI

      10.1186/s13054-015-1132-1

    • NAID

      120005680032

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] 救急隊応答時間とバイスタンダー心肺蘇生効果の関係2017

    • Author(s)
      後藤由和
    • Organizer
      第20回日本臨床救急医学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 8歳以上の小児院外心停止に対する胸骨圧迫のみの心肺蘇生2017

    • Author(s)
      後藤由和
    • Organizer
      第20回日本臨床救急医学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Chest-compression-only bystander cardiopulmonary resuscitation for children with out-of-hospital cardiac arrest.2017

    • Author(s)
      Goto Y
    • Organizer
      European Society of Cardiology Congress 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Chest compression-only cardiopulmonary resuscitation and duration of out-of-hospital cardiac arrest2017

    • Author(s)
      Goto Y
    • Organizer
      European Society of Cardiology Congress 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Duration of bystander-initiated interventions and favourable neurological outcomes in patients with out-of-hospital cardiac arrest2017

    • Author(s)
      Goto Y
    • Organizer
      European Society of Cardiology Congress 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Impact of emergency medical services response time on benefits of bystander-initiated cardiopulmonary resuscitation in patients with out-of-hospital cardiac arrest.2017

    • Author(s)
      Goto Y
    • Organizer
      European Society of Cardiology Congress 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 小児院外心停止に対する胸骨圧迫のみCPRと標準的CPRの転帰比較2017

    • Author(s)
      後藤由和
    • Organizer
      第45回日本救急医学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 小児院外心停止における院外蘇生時間と予後の関係2016

    • Author(s)
      後藤 由和
    • Organizer
      第44回日本救急医学会総会
    • Place of Presentation
      東京
    • Year and Date
      2016-11-17
    • Related Report
      2016 Research-status Report
  • [Presentation] Validation of a termination-of-resuscitation rule for out-of-hospital cardiac arrest in the emergency department2016

    • Author(s)
      Yoshikazu Goto
    • Organizer
      ESC Congress 2016
    • Place of Presentation
      Rome, Itary
    • Year and Date
      2016-08-27
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Age may not be most important factor in the decision to initiate cardiopulmonary resuscitation in the elderly2016

    • Author(s)
      Yoshikazu Goto
    • Organizer
      ESC Congress 2016
    • Place of Presentation
      Rome, Itary
    • Year and Date
      2016-08-27
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Subsequent shock delivery in paediatric out-of-hospital cardiac arrest with initial non-shockable rhythms: a nationwide population-based observational study2016

    • Author(s)
      Yoshikazu Goto
    • Organizer
      ESC Congress 2016
    • Place of Presentation
      Rome, Itary
    • Year and Date
      2016-08-27
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] 小児院外心停止に対する来院時予後予測モデルの検証2016

    • Author(s)
      後藤 由和
    • Organizer
      第30回日本小児救急医学会学術集会
    • Place of Presentation
      仙台
    • Year and Date
      2016-07-02
    • Related Report
      2016 Research-status Report
  • [Presentation] Improvement in Survival With Favorable Neurological Outcome in Elderly Japanese Patients With Out-of-Hospital Cardiac Arrest: A Nationwide Observational Cohort Study2015

    • Author(s)
      Akira Funada, Yoshikazu Goto
    • Organizer
      AHA Scientific Sessions 2015
    • Place of Presentation
      Orand, US
    • Year and Date
      2015-11-07
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 院外心停止に対する蘇生中止基準の検証2015

    • Author(s)
      後藤 由和
    • Organizer
      第43回日本救急医学会総会
    • Place of Presentation
      東京
    • Year and Date
      2015-10-21
    • Related Report
      2015 Research-status Report
  • [Presentation] Duration of resuscitation efforts and survival after out-of-hospital cardiac arrest: an observational study2015

    • Author(s)
      Yoshikazu Goto
    • Organizer
      ESC Congress 2015
    • Place of Presentation
      London, UK
    • Year and Date
      2015-08-29
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Neurological outcomes in children transported to hospital without a prehospital return of spontaneous circulation after out-of-hospital cardiac arrest2015

    • Author(s)
      Yoshikazu Goto
    • Organizer
      ESC Congress 2015
    • Place of Presentation
      London, UK
    • Year and Date
      2015-08-29
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Comparison of biphasic and monophasic waveform defibrillations in out-of-hospital cardiac arrest: an observational cohort study2015

    • Author(s)
      Yoshikazu Goto
    • Organizer
      ESC Congress 2015
    • Place of Presentation
      London, UK
    • Year and Date
      2015-08-29
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Remarks] 金沢大学研究者情報

    • URL

      https://ridb.kanazawa-u.ac.jp/public/detail.php?id=2631

    • Related Report
      2017 Annual Research Report
  • [Remarks] 研究情報(後藤由和)

    • URL

      http://ridb.kanazawa-u.ac.jp/public/detail.php?id=2631&gakusi_cod=30

    • Related Report
      2016 Research-status Report

URL: 

Published: 2015-04-16   Modified: 2019-03-29  

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