Preparation of guidelines for examination and diagnosis of antiphospholipid syndrome.
Project/Area Number |
15K08616
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Laboratory medicine
|
Research Institution | Yamaguchi University |
Principal Investigator |
NOJIMA Junzo 山口大学, 大学院医学系研究科, 教授 (30448071)
|
Co-Investigator(Kenkyū-buntansha) |
家子 正裕 北海道医療大学, 歯学部, 教授 (50250436)
|
Research Collaborator |
MOTOKI Yukari
HARA Kazusa
TAMARI Chikako
|
Project Period (FY) |
2015-04-01 – 2018-03-31
|
Project Status |
Completed (Fiscal Year 2017)
|
Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
Keywords | 抗リン脂質抗体症候群 / 抗カルジオリピン抗体 / 抗β2グリコプロテインⅠ抗体 / ELISA / 抗リン脂質抗体 / ELISAキット / 動脈硬化症 / 酸化ストレス / 全身性エリテマトーデス / 組織因子 / 抗β2-グリコプロテインⅠ抗体 |
Outline of Final Research Achievements |
We tried standardization of antiphospholipid antibodies ELISA in a joint research by three university hospitals participating in the Japan Antiphospholipid antibodies standardization workshop. Regarding the ten kinds of ELISA kits commercially available in Japan, we determined the reference range of healthy subjects. Furthermore, we clarified the combination of ELISA kits most suitable for the diagnosis of antiphospholipid syndrome.
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Report
(4 results)
Research Products
(43 results)
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[Journal Article] Hydrogen-rich water for improvements of mood, anxiety, and autonomic nerve function in daily life.2018
Author(s)
Mizuno K, Sasaki AT, Ebisu K, Tajima K, Kajimoto O, Nojima J, Kuratsune H, Hori H, Watanabe Y
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Journal Title
Med Gas Res.
Volume: 7
Issue: 4
Pages: 247-255
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] A potential biomarker for fatigue: Oxidative stress and anti-oxidative activity.2016
Author(s)
Fukuda, S., Nojima, J., Motoki, Y., Yamaguti, K., Nakatomi, Y., Okawa, N., Fujiwara, K., Watanabe, Y., Kuratsune, H.
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Journal Title
Biol. Psychol.
Volume: 118
Pages: 88-93
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Ubiquinol-10 supplementation improves fatigue, autonomic nervous function, and cognitive function in patients with chronic fatigue syndrome: An open-label study and a randomized, double-blind, placebo-controlled study.2016
Author(s)
Fukuda, S., Nojima, J., Kajimoto, O., Yamaguti, K., Nakatomi, Y., Kuratsune, H., Watanabe, Y.
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Journal Title
Biofactors
Volume: 8
Issue: 4
Pages: 431-440
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] The production of coagulation factor VII by adipocytes is enhanced by tumor necrosis factor-α or isoproterenol2015
Author(s)
N Takahashi, T Yoshizaki, N Hiranaka, O Kumano, T Suzuki, M Akanuma, T Yui, K Kanazawa, M Yoshida, S Naito, M Fujiya, Y Kohgo, M Ieko
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Journal Title
International Journal of Obesity
Volume: 39
Issue: 5
Pages: 747-754
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
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