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Diagnosis and treatment of psychological pain from a view of somatosensory amplification

Research Project

Project/Area Number 15K08681
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Pain science
Research InstitutionInternational University of Health and Welfare (2018)
Teikyo University (2015-2017)

Principal Investigator

Nakao Mutsuhiro  国際医療福祉大学, 医学部, 教授 (80282614)

Co-Investigator(Kenkyū-buntansha) 竹内 武昭  東邦大学, 医学部, 准教授 (60453700)
城月 健太郎  武蔵野大学, 人間科学部, 准教授 (50582714)
Project Period (FY) 2015-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywordsストレス / 心身症 / 心因性疼痛 / 心身性疼痛
Outline of Final Research Achievements

Psychosomatic patients often complain of a variety of somatic pain symptoms of unknown origin. The study clarified the role of clinical predictors of complaints of somatic symptoms. We enrolled 604 outpatients visiting a psychosomatic outpatient clinic. The outcome was the total number of somatic symptoms, and the candidate clinical predictors were perceived psychosocial stress, alexithymia, somatosensory amplification, adaptation, anxiety, and depression. All participants completed questionnaires assessing the outcome and the predictors. As results, the average number of reported somatic symptoms was 4.8; the most frequent was fatigue, followed by insomnia, low-back pain, headache, and palpitations. Structural equation models indicated links between excessive adaptation (via perceived psychosocial stress, alexithymia, and somatosensory amplification) and the total number of somatic symptoms.

Academic Significance and Societal Importance of the Research Achievements

患者が持続的な疼痛を訴えていて十分な検査をしているにも関わらず、その症状を説明するだけの器質的・機能的所見が得られない病態は、各科で個別に対応がなされ学術的な知見が重ねられてきた。本研究では身体感覚増幅という1つの概念によって統一的に病態を説明・理解しようとする試みが独創的であり、そのエビデンスはまだ非常に限られている。身体感覚増幅の概念によって精神・心理的疼痛の知見を重ねることができた。「機能性身体症候群(functional somatic syndromes)」として新たな診断基準作りに寄与することもできる。

Report

(5 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (21 results)

All 2018 2017 2016 2015

All Journal Article (9 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 7 results,  Open Access: 4 results) Presentation (8 results) (of which Int'l Joint Research: 3 results,  Invited: 6 results) Book (4 results)

  • [Journal Article] Alexithymia and Somatosensory Amplification Link Perceived Psychosocial Stress and Somatic Symptoms in Outpatients with Psychosomatic Illness.2018

    • Author(s)
      Nakao M, Takeuchi T
    • Journal Title

      Journal of Clinical Medicine

      Volume: 7 Issue: 5 Pages: 112-112

    • DOI

      10.3390/jcm7050112

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Somatic manifestation of distress: clinical medicine, psychological, and public health perspectives.2017

    • Author(s)
      Nakao M
    • Journal Title

      Biopsychosocial Medicine

      Volume: 11 Issue: 1 Pages: 33-33

    • DOI

      10.1186/s13030-017-0119-3

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Relationships between catastrophic thought, bodily sensations and physical symptoms.2017

    • Author(s)
      Seto H, Nakao M.
    • Journal Title

      Biopsychosocial Medicine

      Volume: 11 Issue: 1 Pages: 28-28

    • DOI

      10.1186/s13030-017-0110-z

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Brief internet-based cognitive behavior therapy program with a supplement drink improved anxiety and somatic symptoms in Japanese workers.2017

    • Author(s)
      Shirotsuki K, Nonaka Y, Takano J, Abe K, Adachi SI, Adachi S, Nakao M.
    • Journal Title

      Biopsychosocial Medicine

      Volume: 11 Issue: 1 Pages: 25-25

    • DOI

      10.1186/s13030-017-0111-y

    • Related Report
      2017 Research-status Report
    • Open Access
  • [Journal Article] Clinical characteristics and referral patterns of outpatients visiting a Japanese psychosomatic medicine clinic.2016

    • Author(s)
      Nakao M, Takeuchi T.
    • Journal Title

      International Journal of Behavioral Medicine

      Volume: 23 Issue: 5 Pages: 580-588

    • DOI

      10.1007/s12529-015-9520-0

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] 難治性末梢性めまいの重症度に影響する心理社会的要因の検討.2016

    • Author(s)
      五島史行, 野村恭子, 中尾睦宏, 瀬戸泰.
    • Journal Title

      心身医学

      Volume: 56 Pages: 148-156

    • NAID

      130005128352

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Clinical characteristics and referral patterns of outpatients visiting a Japanese psychosomatic medicine clinic.2015

    • Author(s)
      Mutsuhiro Nakao, Takeaki Takeuchi
    • Journal Title

      International Journal of Behavioral Medicine

      Volume: Nov. 20

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] 心身症概念の変遷:「身体症状症および関連症群(身体表現性障害)」から「機能性身体症候群」まで2015

    • Author(s)
      中尾睦宏
    • Journal Title

      臨床精神薬理

      Volume: 18 Pages: 371-379

    • Related Report
      2015 Research-status Report
  • [Journal Article] 機能性身体症候群と心身相関:身体感覚増幅と身体感覚に対する破局的思考2015

    • Author(s)
      瀬戸泰、中尾睦宏
    • Journal Title

      日本心療内科学会誌

      Volume: 19 Pages: 170-177

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Presentation] Bio-Psycho-Socialモデルに基づくチーム医療の実践:UPMが貢献できる点と課題となる点2018

    • Author(s)
      中尾睦宏
    • Organizer
      日本心理医療諸学会連合(UPM)第31回大会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 生活習慣病と不眠.2017

    • Author(s)
      中尾睦宏
    • Organizer
      第51回日本成人病学会学術集会
    • Place of Presentation
      都市センターホテル: 東京, 日本
    • Year and Date
      2017-01-14
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] 心身医学研究でエビデンスを蓄積する意義.2017

    • Author(s)
      中尾睦宏
    • Organizer
      第58回日本心身医学会総会, 札幌
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] Selection of diagnostic cut-off points considering costs of false diagnoses in three-group classification applied to pre-disease condition screening.2017

    • Author(s)
      KazueYamaoka, Yoshiaki Nakata, Mutsuhiro Nakao, Kei Asayama, Mariko Inoue, Toshiro Tango.
    • Organizer
      XXIXth International Biometric Conference (29th IBC), Barcelona, Spain
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] The effect of brief internet-based cognitive behaviour therapy with supplement drink on psychological factors in Japanese workers.2016

    • Author(s)
      Kentaro Shiotsuki, Yuji Nonaka, Jiro Takano, Keiichi Abe, Shohei Adachi, Souichiro Adachi, Mutsuhiro Nakao.
    • Organizer
      The 17th Asian Congress on Psychosomatic Medicine, Fukuoka, Japan
    • Place of Presentation
      九州大学医学部講堂: 福岡, 日本
    • Year and Date
      2016-08-21
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] How to develop behavioral health in Asia2016

    • Author(s)
      Mutsuhiro Nakao
    • Organizer
      International Behavioral Health Conference 2016
    • Place of Presentation
      Hong Kong, China
    • Year and Date
      2016-01-16
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] 行動医学の推進とコアカリキュラム2015

    • Author(s)
      中尾睦宏
    • Organizer
      第22回日本行動医学会学術総会
    • Place of Presentation
      仙台
    • Year and Date
      2015-10-17
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 身体疾患とうつ病2015

    • Author(s)
      中尾睦宏
    • Organizer
      第56回日本心身医学会総会
    • Place of Presentation
      幕張
    • Year and Date
      2015-06-27
    • Related Report
      2015 Research-status Report
    • Invited
  • [Book] 「はたらく」を支える!女性のメンタルヘルス2017

    • Author(s)
      中尾睦宏(編集:丸山総一郎)
    • Total Pages
      404
    • Publisher
      南山堂
    • ISBN
      9784525181710
    • Related Report
      2017 Research-status Report
  • [Book] ヘルスサービスリサーチ入門2017

    • Author(s)
      中尾睦宏(編集:田宮菜奈子、小林廉毅)
    • Total Pages
      257
    • Publisher
      東京大学出版会
    • ISBN
      9784130624190
    • Related Report
      2017 Research-status Report
  • [Book] うつ病の臨床:現代の病理と最新の治療2016

    • Author(s)
      中尾睦宏(編集:神庭重信)
    • Total Pages
      232
    • Publisher
      最新医学社
    • Related Report
      2016 Research-status Report
  • [Book] 行動医学テキスト2015

    • Author(s)
      野村忍、島津明人、堤明純、中尾睦宏、吉内一浩(編集)
    • Total Pages
      248
    • Publisher
      中外医学社
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2020-03-30  

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