| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Outline of Final Research Achievements |
Partial volume effect is inevitable phenomena in positron emission tomography (PET)imaging and degrade the quantification of PET images. Partial volume correction (PVC) will improve the quantification of PET images under the perfect condition which is difficult in real clinical study. We aimed to investigate error-propagation properties of PVC algorithms and know properties of PVCs on clinical PET images.
We found that the even small error sources (eg. image-registration, segmentation), this surely propagate to the outcome and its amount is not small. In clinical data, different PVC algorithms provided difference amount of recovery and this tendency was also different among subject conditions. PVC is very sensitive with the mismatch between anatomy and PET images, so hybrid algorithms would be suitable for practical and robust PVC rather than anatomy-based method.
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