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Quantitative evaluation and calibration of PET scanners using traceable point-like sources

Research Project

Project/Area Number 15K08701
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical Physics and Radiological Technology
Research InstitutionKitasato University

Principal Investigator

Hasegawa Tomoyuki  北里大学, 医療衛生学部, 教授 (10276181)

Co-Investigator(Renkei-kenkyūsha) SATO YASUSHI  産業技術総合研究所, 計測標準研究部門, 研究員 (90357153)
ODA KEIICI  北海道科学大学, 教授 (70224235)
WADA YASUHIRO  理化学研究所, 生命機能化学研究センター, 副チームリーダー (40382197)
INOUE YUSUKE  北里大学, 医学部, 教授 (40232566)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
KeywordsPET / 点状線源 / 校正 / 定量性 / 品質管理 / 医学物理 / PET装置 / 陽電子断層撮像法(PET)
Outline of Final Research Achievements

Positron emission tomography (PET) plays an important role in diagnostic imaging and molecular imaging researches. Its utility is supported by physical quality control of PET scanners, among which the most important is quantitative evaluation and calibration. However, with the conventional method using a phantom and a dose calibrator, its reliability and convenience were limited. In this research, we developed novel traceable point-like sources, evaluation and calibration protocols using them, promoting multicenter studies on a total of 13 models in Japan, and revealed the usefulness of the proposed method.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (15 results)

All 2017 2016 2015

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (14 results) (of which Int'l Joint Research: 3 results,  Invited: 2 results)

  • [Journal Article] Evaluation of spatial dependence of point spread function-based PET reconstruction using a traceable point-like 22Na source2016

    • Author(s)
      T. Murata, K. Miwa, N. Miyaji, K. Wagatsuma, T. Hasegawa, K. Oda, T. Umeda, T. Iimori, Y. Masuda, T. Terauchi, M. Koizumi
    • Journal Title

      EJNMMI Physics

      Volume: 3 Issue: 1 Pages: 26-26

    • DOI

      10.1186/s40658-016-0162-3

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] トレーサブル点状線源を用いる定量性評価校正法の開発状況報告2017

    • Author(s)
      長谷川 智之、小山翔司、宮武比呂樹、菊池 敬、井上 優介、佐藤 泰、我妻 慧、織田 圭一、和田康弘、三輪健太
    • Organizer
      第57回日本核医学会学術大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] トレーサブル68Ge/68Ga点状線源を用いるPET装置の校正法2017

    • Author(s)
      小山翔司, 長谷川智之, 井上優介, 菊池 敬, 宮武比呂樹, 我妻 慧, 宮司典明, 渡部浩司, 志田原美保, 四月朔日聖一, 津田啓介, 村松禎久, 栁澤かおり, 和田康弘, 織田圭, 佐藤 泰
    • Organizer
      第37回日本核医学技術学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Point-like Ge-68/Ga-68 radioactive source with a spherical acrylic absorber as a basic calibration tool for PET scanners2017

    • Author(s)
      Tomoyuki Hasegawa, Shoji Koyama, Takahiro Yamada, Mikio Matsumoto, Hidetake Ishizu, Takahiro Mikamoto, Yasushi Sato, Hiroki Miyatake, Kei Kikuchi, Yusuke Inoue
    • Organizer
      Japan-Korea Joint Meeting on Medical Physics (JKMP)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Spherical and cylindrical ROIs in the calibration method with a traceable Ge-68/Ga-68 point-like source2017

    • Author(s)
      S. Koyama, T. Hasegawa, Y. Inoue, K. Kikuchi, H. Miyatake, K. Wagatsuma, N. Miyaji, H. Watabe, M. Shidahara
    • Organizer
      Japan-Korea Joint Meeting on Medical Physics (JKMP)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Geant4によるPETとトレーサブル点状線源のシミュレーション2017

    • Author(s)
      長谷川智之
    • Organizer
      第37回日本核医学技術学会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 球形状アクリル吸収体トレーサブルGe-68/Ga-68点状線源を用いたPET装置校正2016

    • Author(s)
      小山翔司、安藤 瞭、外山 舜、長谷川智之、宮武比呂樹、菊池 敬、井上優介、我妻 慧、織田圭一、佐藤 泰、山田崇裕
    • Organizer
      第101回日本医学物理学会学術大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Related Report
      2016 Research-status Report
  • [Presentation] Detailed analysis of calibration data obtained using a traceable Ge-68/Ga-68 point-like source for clinical PET scanners2016

    • Author(s)
      S. Koyama, T. Hasegawa, K. Kikuchi, Y. Inoue, H. Miyatake, K. Wagatsma, K. Oda, Y. Sato, T. Yamada
    • Organizer
      第112回日本医学物理学会学術大会
    • Place of Presentation
      沖縄コンベンションセンター(沖縄県宜野湾市)
    • Related Report
      2016 Research-status Report
  • [Presentation] トレーサブルGe-68/Ga-68点状線源に関わる位置依存性の基本的評価2016

    • Author(s)
      小山翔司、安藤 瞭、外山 舜、長谷川智之、宮武比呂樹、菊池 敬、井上優介、我妻 慧、織田圭一、佐藤 泰、山田崇裕
    • Organizer
      第44回日本放射線技術学会秋季学術大会
    • Place of Presentation
      大宮ソニックシティ(埼玉県さいたま市)
    • Related Report
      2016 Research-status Report
  • [Presentation] トレーサブル点状線源を用いる定量性評価校正法2016

    • Author(s)
      長谷川智之、小山翔司、宮武比呂樹、菊池 敬、井上優介、佐藤 泰、我妻 慧、織田圭一、和田康弘、三輪健太、村田泰輔
    • Organizer
      第56回日本核医学会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Related Report
      2016 Research-status Report
  • [Presentation] アクリル吸収体トレーサブルGe-68/Ga-68点状線源を用いる定量性評価校正法2015

    • Author(s)
      長谷川智之、宮武比呂樹、菊池 敬、井上優介、佐藤 泰、山田崇裕、織田圭一、和田康弘、坂口和也、安藤 瞭、外山 舜
    • Organizer
      第55回日本核医学会
    • Place of Presentation
      ハイアットリージェンシー東京(東京都新宿区)
    • Year and Date
      2015-11-05
    • Related Report
      2015 Research-status Report
  • [Presentation] Novel Traceable Point-like Ge-68/Ga-68 Source with a Spherical Acrylic Absorber for Calibration and Evaluation of PET Scanners2015

    • Author(s)
      T. Hasegawa, H. Miyatake, T. Yamada, Y. Sato, K. Kikuchi, Y. Inoue, K. Oda
    • Organizer
      IEEE Medical Imaging Conference
    • Place of Presentation
      Town & Country Hotel (San Diego, CA, USA)
    • Year and Date
      2015-11-04
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 二機種での長期間にわたるトレーサブルNa-22点状線源の測定報告2015

    • Author(s)
      宮武比呂樹、長谷川智之、阿部 豊、菊池 敬、井上優介
    • Organizer
      第43回日本放射線技術学会秋季学術大会
    • Place of Presentation
      金沢市文化ホール(石川県金沢市)
    • Year and Date
      2015-10-08
    • Related Report
      2015 Research-status Report
  • [Presentation] 研究計画および論文作成上の注意事項2015

    • Author(s)
      長谷川智之
    • Organizer
      第110回日本医学物理学会
    • Place of Presentation
      共済ホール(北海道札幌市)
    • Year and Date
      2015-09-19
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] トレーサブル点状線源を用いるPET定量性評価・校正法におけるアクリルGe-68/Ga-68点状線源の導入2015

    • Author(s)
      長谷川智之,山田崇裕,佐藤 泰,織田圭一,和田康弘,宮武比呂樹,菊池 敬
    • Organizer
      第109回日本医学物理学会学術大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2015-04-16
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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