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Developments of the evaluation criteria of the quality of treatment plans and automatic treatment planning algorithms for high-precision radiotherapy

Research Project

Project/Area Number 15K08702
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical Physics and Radiological Technology
Research InstitutionJuntendo University

Principal Investigator

Sugimoto Satoru  順天堂大学, 医学(系)研究科(研究院), 准教授 (00373316)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Keywords高精度放射線治療 / 自動治療計画 / 全乳房照射 / フィールド・イン・フィールド法 / 線量不確かさ / 放射線治療 / ETC法 / 乳房術後照射 / Field-in-Field法 / 強度変調放射線治療
Outline of Final Research Achievements

Recent advancement of radiation therapy irradiation technique has enabled us to concentrate more radiation dose to malignant tumors and spare exposure to surrounding normal tissues simultaneously than before. The advancement of radiation therapy has induced the complication of treatment plans, which makes the evaluation of the quality of them difficult, and the increase of the time cost of making them. The purposes of this study are the developments of the quality evaluation criteria for treatment plans and automatic treatment planning algorithms referring them for high-precision radiotherapy.
We developed the semi-automatic treatment planning algorithms for high-precision whole-breast irradiation techniques. The quality evaluation criteria we adopted turned to take much time to calculate than expected and, therefore, we could not implement them into the automatic treatment planning algorithms.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (6 results)

All 2017 2016 2015

All Journal Article (1 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 1 results) Presentation (5 results)

  • [Journal Article] Limited Impact of Setup and Range Uncertainties, Breathing Motion, and Interplay Effects in Robustly Optimized Intensity Modulated Proton Therapy for Stage III Non-small Cell Lung Cancer2016

    • Author(s)
      T. Inoue, J. Widder, L.V. van Dijk, H. Takegawa, M. Koizumi, M. Takashina, K. Usui, C. Kurokawa, S. Sugimoto, A.I. Saito, K. Sasai, A.A. van't Veld, J.A. Langendijk, E.W. Korevaar
    • Journal Title

      International Journal of Radiation Oncology, Biology, Physics

      Volume: 96 Issue: 3 Pages: 661-669

    • DOI

      10.1016/j.ijrobp.2016.06.2454

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Presentation] Semi-automatic fluence modification method to reduce hot spots for electronic irregular surface compensation2017

    • Author(s)
      Sugimoto S, Watanabe H, Kawabata T
    • Organizer
      AAPM 59th Annual Meeting & Exhibition
    • Related Report
      2017 Annual Research Report
  • [Presentation] Feasibility study of a semi-automatic treatment planning algorithm for breast irradiation using the field-in-field technique2017

    • Author(s)
      Sugimoto S, Watanabe H, Kawabata T
    • Organizer
      8th Japan-Korea Meeting on Medical Physics
    • Related Report
      2017 Annual Research Report
  • [Presentation] Deblurring measured radiation profile using a Gaussian expansion method with a regularization term of first derivative2016

    • Author(s)
      S. Sugimoto, T. Inoue, C. Kurokawa, K. Usui
    • Organizer
      第111回日本医学物理学会学術大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-04-14
    • Related Report
      2016 Research-status Report 2015 Research-status Report
  • [Presentation] Evaluation of the statistical dose-uncertainty in prostate VMAT2016

    • Author(s)
      Tatsuya Inoue, Satoru Sugimoto, Chie Kurokawa, Hironori Nagata, Toru Kawabata, Kana Ito, Anneyuko Saito, Yataro Horikawa, Keisuke Sasai
    • Organizer
      第111回日本医学物理学会学術大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-04-14
    • Related Report
      2015 Research-status Report
  • [Presentation] 照射野プロファイルのGaussian基底展開とその応用の検討2015

    • Author(s)
      杉本聡、黒河千恵、井上達也、臼井桂介
    • Organizer
      第110回日本医学物理学会学術大会
    • Place of Presentation
      北海道大学
    • Year and Date
      2015-09-18
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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