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Development of suitable technique of respiratory gating spot scanning proton therapy and establishment of its standarlization

Research Project

Project/Area Number 15K08705
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical Physics and Radiological Technology
Research InstitutionFujita Health University

Principal Investigator

Hayashi Naoki  藤田保健衛生大学, 保健学研究科, 准教授 (00549884)

Research Collaborator YASUI Keisuke  名古屋陽子線治療センター, 医学物理士
UESHIMA Yusuke  藤田保健衛生大学, 大学院
NAKAGAMI Chikae  藤田保健衛生大学, 大学院
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords陽子線治療 / 呼吸性移動 / スポットスキャニング / シミュレーション / 独立検証 / 体表面監視
Outline of Final Research Achievements

The purpose of this study is to develop suitable technique of respiratory gating spot scanning proton therapy (RG-SSPT). In this research term, we have carried out 3 contents: Monte Carlo simulation for RG-SSPT, development of respiratory management system by monitoring patient body surface, development of in-house program for independent dose verification system for RG-SSPT. As results, RG-SSPT hardly produced scattered radiation in system unit. Due to patient surface observation and analysis, we estimated suitable monitoring region for RG-SSPT. Then we could analyze respiratory signal continuously. With in-house independent dose verification program, we could estimate/verify dose distribution of RG-SSPT.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (13 results)

All 2018 2017 2016 2015

All Journal Article (4 results) (of which Int'l Joint Research: 4 results,  Peer Reviewed: 4 results,  Open Access: 3 results) Presentation (9 results) (of which Int'l Joint Research: 7 results,  Invited: 1 results)

  • [Journal Article] Evaluation of dosimetric advantages of using patient-specific aperture system with intensity-modulated proton therapy for the shallow depth tumor.2018

    • Author(s)
      Yasui K, Toshito T, Omachi C, Hayashi K, Tanaka K, Asai K, Shimomura A, Muramatsu R, Hayashi N
    • Journal Title

      Journal of applied clinical medical physics

      Volume: 19 Issue: 1 Pages: 132-137

    • DOI

      10.1002/acm2.12231

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Mathematical models and simlations of glioblastoma invation.2017

    • Author(s)
      Akisato Kubo, Yuto Miyata, Hidetoshi Kobayashi, Naoki Hayashi
    • Journal Title

      International Journal of Mathematical Models and Methods in Applied Sciences

      Volume: 11 Pages: 107-116

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Nonlinear Evolution Equations and Its Application to a Tumour Invasion Model2016

    • Author(s)
      Akisato Kubo, Yuto Miyata, Hidetoshi Kobayashi, Hiroki Hoshino, Naoki Hayashi
    • Journal Title

      Advances in Pure Mathematics

      Volume: 6 Pages: 878-893

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Characterization of stochastic noise and post-irradiation density growth for reflective-type radiochromic film in therapeutic photon beam dosimetry.2016

    • Author(s)
      Kamomae T, Oita M, Hayashi N, Sasaki M, Aoyama H, Oguchi H, Kawamura M, Monzen H, Itoh Y, Naganawa S
    • Journal Title

      Physica medica

      Volume: 32 Pages: 1314-1320

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Presentation] Respiratory motion management on patient body surface using 3D scanning technology2017

    • Author(s)
      Chikae Nakagami, Naoki Hayashi, Takuma Matsunaga, Yumiko Adachi, Masashi Nozue, H Yamamoto, Y Shirakami
    • Organizer
      The 59th annual meeting of American Association of Physicists in Medicine
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Development of independent dose verification program considering respiratory movement in spot scanning proton therapy2017

    • Author(s)
      Yusuke Ueshima, Naoki Hayashi, Keisuke Yasui
    • Organizer
      The 59th annual meeting of American Association of Physicists in Medicine
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Additional exposure on out-of-target lesion due to dynamic tumor tracking irradiation2017

    • Author(s)
      Naoki Hayashi, Mayu Kokawaji, Masaya Kobayashi, Yuya Katsuragawa, Koudai Kimura, Chikae Nakagami, Yusuke Ueshima, Yuma Takada, Shingo Tanahashi
    • Organizer
      The 59th annual meeting of American Association of Physicists in Medicine
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Accuracy and precision of dynamic tracking irradiation with VERO-4DRT system2016

    • Author(s)
      Naoki Hayashi, Yuma Takada, Tsutomu Mizuno, Hiroki Nakae, Taro Murai
    • Organizer
      The 58th annual meeting of American Association of Physicists in Medicine
    • Place of Presentation
      Washington DC
    • Year and Date
      2016-07-31
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] 表計算ソフトを用いた品質管理結果の統計的管理法2015

    • Author(s)
      林 直樹
    • Organizer
      2016年度愛知県放射線治療研究会
    • Place of Presentation
      藤田保健衛生大学病院(愛知県,豊明市)
    • Year and Date
      2015-12-06
    • Related Report
      2015 Research-status Report
  • [Presentation] 放射線治療の最新技術と関連領域との横断的研究2015

    • Author(s)
      林 直樹
    • Organizer
      第43回日本放射線技術学会秋季大会
    • Place of Presentation
      金沢市文化会館(石川県、金沢市)
    • Year and Date
      2015-10-08
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] Field-in-field irradiation for breast cancer with VERO-4DRT system: a feasibility study.2015

    • Author(s)
      Naoki Hayashi, Yuma Takada, Tsutomu Mizuno, Toru Itoh
    • Organizer
      The 57th annual meeting of American Association of Physicists in Medicine.
    • Place of Presentation
      Anaheim Convention Center (California)
    • Year and Date
      2015-07-12
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Fundamental verification of respiratory-gated spot scanning proton beam therapy.2015

    • Author(s)
      Hamano H, Hayashi N, Yamakawa T, Yasui K, Kato H.
    • Organizer
      The 57th annual meeting of American Association of Physicists in Medicine.
    • Place of Presentation
      Anaheim Convention Center (California)
    • Year and Date
      2015-07-12
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] The simple monitor unit calculation for irregular field in passive proton beam.2015

    • Author(s)
      Yamakawa T, Hayashi N, Hamano H, Yasui K, Kato H.
    • Organizer
      The 57th annual meeting of American Association of Physicists in Medicine.
    • Place of Presentation
      Anaheim Convention Center (California)
    • Year and Date
      2015-07-12
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research

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Published: 2015-04-16   Modified: 2019-03-29  

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