Feasibility study of Compton PET scanner

• Project/Area Number: 15K08708
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Medical Physics and Radiological Technology
• Research Institution: National Institutes for Quantum and Radiological Science and Technology
• Principal Investigator: Eiji Yoshida 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所 計測・線量評価部, 主幹研究員(定常) (50392246)
• Project Period (FY): 2015-04-01 – 2019-03-31
• Project Status: Completed (Fiscal Year 2018)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2016: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000); Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
• Keywords: PET / コンプトンカメラ / ３次元検出器

Outline of Final Research Achievements

PET detectors have high high performance of sensitivity and spatial resolution. PET detectors can be further improved by tracking the interaction of gamma ray by using Compton camera. In this work, we developed the new Compton tracking PET detector. This detector consist of the scatterer part of the GAGG array and the MPPC array and the absorber part of the GSO array and the PS-PMT. For scatterer part, 0.9 mm scintillator can be identified easily and energy resolution was 15%. The developed detector promises high performance for single gamma based medical imaging.

Academic Significance and Societal Importance of the Research Achievements

コンプトンカメラはすでに天体や環境放射能の測定において応用されているが，医療利用に関しては検出効率が最大の欠点となっているのが現状である。開発した検出器を用いてコンプトンカメラの技術を補助的に利用することで従来のPETでは利用できなかった入射角度という新たな情報を利用してPET計測の更なる性能向上に寄与するものと期待できる。また，PETの技術をコンプトンカメラに応用することで高感度なシングルガンマ・イメージングにつながると期待する。

Research Products

• [Int'l Joint Research] ミュンヘン大学(ドイツ)
• [Int'l Joint Research] スタンフォード大学(米国)
• [Int'l Joint Research] ミュンヘン大学(ドイツ)
• [Int'l Joint Research] スタンフォード大学(米国)
• [Int'l Joint Research] ミュンヘン大学(ドイツ)
• [Presentation] Sensitivity improvement in 44Sc whole gamma imaging: simulation study (2018)
  • Author(s): Yusuke Okumura, Eiji Yoshida, Hideaki Tashima, Mikio Suga, Naoki Kawachi, Katia Parodi, Taiga Yamaya
  • Organizer: IEEE NSS-MIC2018
  • Int'l Joint Research
• [Presentation] Development of the 4-Layer GAGG DOI Detector for a Scatterer of Compton Camera (2018)
  • Author(s): Sodai Takyu, Eiji Yoshida, Naoko Inadama, Fumihiko Nishikido, Munetaka Nitta, Kei Kamada, Katia Parodi, Taiga Yamaya
  • Organizer: IEEE NSS-MIC2018
  • Int'l Joint Research
• [Presentation] Concrete realization of the whole gamma imaging concept (2017)
  • Author(s): Eiji Yoshida, Hideaki Tashima, Yusuke Okumura, Mikio Suga, Naoki Kawachi, Kei Kamada, Katia Parodi, Taiga Yamaya
  • Organizer: IEEE NSS-MIC2017
  • Int'l Joint Research
• [Presentation] 新しいコンプトンPET装置の3ガンマイメージングシミュレーション (2017)
  • Author(s): 奥村 勇介, 吉田 英治, 田島 英朗, 菅 幹生, 河地 有木, パロディ カティア, 山谷 泰賀
  • Organizer: 第78回 応用物理学会 秋季学術講演会
• [Presentation] Whole gamma imaging (WGI) concept: simulation study of triple-gamma imaging (2017)
  • Author(s): Taiga Yamaya, Eiji Yoshida, Hideaki Tashima, Atsushi Tsuji, Kotaro Nagatsu, Mitsutaka Yamaguchi, Naoki Kawachi, Yusuke Okumura, Mikio Suga, Katia Parodi
  • Organizer: SNMMI2017 Annual Meeting
  • Int'l Joint Research
• [Presentation] Sensitivity and Spatial Resolution Simulation of a PET-Compton Insert Imaging System (2016)
  • Author(s): E.Yoshida, H.Tashima, C.S.Levin, K.Parodi, T.Yamaya
  • Organizer: 2016 IEEE Nuc. Sci. Sympo. & Med. Imag. Conf
  • Place of Presentation: Convention center, Strasbourg, France
  • Year and Date: 2016-10-30
  • Int'l Joint Research
• [Presentation] Geant4 Simulation Study of a Compton-PET imaging system using advanced 3D positioning detectors (2016)
  • Author(s): J.Jiang, E.Yoshida, H.Tashima, K.Shinohara , M.Suga, T.Yamaya
  • Organizer: 第111回日本医学物理学会学術大会
  • Place of Presentation: 神奈川県 横浜市 パシフィコ横浜
  • Year and Date: 2016-04-14
• [Presentation] Geant4 simulation study of a compton-PET imaging system using advanced 3D positioning detectors (2016)
  • Author(s): Jianyong Jiang, 吉田英治, 田島英朗, 篠原滉平, 菅幹生, 山谷泰賀
  • Organizer: 第111回日本医学物理学会学術大会
  • Place of Presentation: 横浜
  • Year and Date: 2016-04-14
• [Presentation] 多層検出器を用いたコンプトンPETの実現可能性の検討 (2016)
  • Author(s): 篠原滉平, 菅幹生, 吉田英治, 田島英朗, Jiang Jianyong, Ahmed Abdella Mohammednur, 山谷泰賀
  • Organizer: 日本医用画像工学会 JAMITフロンティア2016
  • Place of Presentation: 那覇
  • Year and Date: 2016-01-19
• [Presentation] imulation Study of a DOI-Based PET-Compton Imaging System for Positron Emitters (2015)
  • Author(s): E. Yoshida, H. Tashima, C. S. Levin, K. Parodi, T. Yamaya
  • Organizer: IEEE Nuc. Sci. Sympo. & Med. Imag. Conf
  • Place of Presentation: San Diego, USA
  • Year and Date: 2015-10-01
  • Int'l Joint Research
• [Presentation] 高感度コンプトンPETに向けた基礎的検討 (2015)
  • Author(s): 吉田英治, 田島英朗,山谷泰賀
  • Organizer: 第110回日本医学物理学会学術大会
  • Place of Presentation: 札幌
  • Year and Date: 2015-09-18