| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Outline of Final Research Achievements |
Supported by Grant-in-Aid for Scientific Research C, this researcher conducted a Mendelian randomization analysis for the association of pre-diagnostic plasma adipokine levels with colorectal cancer risk. This researcher observed a positive association between plasma leptin levels and colorectal cancer risk after controlling for known confounding factors. Of interest, the Mendelian randomization analysis revealed that an observed association was not fully explained by unknown confounding factors. These results should be interpreted in light of several limitations of the Mendelian randomization analysis, and further studies are needed to confirm the findings of this study.
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