| Project/Area Number |
15K08752
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Epidemiology and preventive medicine
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| Research Institution | Nippon Medical School |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
川田 智之 日本医科大学, 大学院医学研究科, 大学院教授 (00224791)
小谷 英太郎 日本医科大学, 医学部, 講師 (10287708)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2016: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2015: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
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| Keywords | メタボリック症候群 / 多価不飽和脂肪酸 / 疫学研究 / コホート研究 / メタボリックシンドローム / 不飽和脂肪酸 / 中年男性 / 予防医学 / 危険因子 |
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| Outline of Final Research Achievements |
Metabolic syndrome (MetS) is well known to be a major risk factor for cardiovascular disease, not only in Western countries but also in Japan. It is therefore important to prevent new-onset MetS to further support health promotion for Japanese people. We conducted worksite-based epidemiological study to examine whether serum ω-3 polyunsaturated fatty acid levels were predictive of new-onset MetS in Japanese workingmen. However, any polyunsaturated fatty acid levels measured in this study (eicosapentaenoic acid, docosahexaenoic acid, and eicosapentaenoic acid/arachidonic acid ratio) did not show significant predictive values for new-onset MetS in this study population. Further studies are needed to elucidate the longitudinal association between ω-3 polyunsaturated fatty acid levels and the risk of new-onset MetS.
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