Molecular nutritional study for prevention of prostate cancer
Project/Area Number |
15K08779
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Hygiene and public health
|
Research Institution | Kumamoto University |
Principal Investigator |
Katoh Takahiko 熊本大学, 大学院生命科学研究部(医), 教授 (70169506)
|
Project Period (FY) |
2015-04-01 – 2018-03-31
|
Project Status |
Completed (Fiscal Year 2017)
|
Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
Keywords | 前立腺がん / 栄養 / 食物摂取頻度調査票 / 分子疫学 / ヘテロサイクリックアミン / 遺伝子多型 / 食物摂取頻度調査 |
Outline of Final Research Achievements |
We conducted a comprehensive molecular nutrition epidemiological analysis to clarify the risk factors for prostate cancer in Japanese population. These finding indicate that high heterocyclic aromatic amines intake is a risk factors of prostate cancer in Japanese men, and that the genotypes of N-acetyltransferase 2, Cytochrome P450CYP1A1, and Cytochrome P4501A2 may affect the degree of cancer risk via changes in heterocyclic aromatic amines -metabolizing enzymes.
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Report
(4 results)
Research Products
(5 results)