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Disparities, dynamic changes, and controls of burden of cardiovascular diseases and cancer in Japan, China, and Taiwan

Research Project

Project/Area Number 15K08800
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Hygiene and public health
Research InstitutionFukushima Medical University (2017-2018)
University of Tsukuba (2015-2016)

Principal Investigator

Ma Enbo  福島県立医科大学, 公私立大学の部局等, 准教授 (00590770)

Project Period (FY) 2015-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywordsyear of life lost / burden of disease / trend / cardiovascular disease / cancer / Japan / China / Taiwan / stroke / heart disease / chronic disease / years of life lost / trends / ischemic heart disease / lifestyle factor
Outline of Final Research Achievements

Due to the stroke mortality, the years of life lost (YLL), average of YLL per year, and YLL rates in the past 30 years were similar between Japan and Taiwan. Prominent decline of stroke mortality was seen in the hemorrhagic stroke, but not in the cerebral infarction in Japanese populations. The decline of YLLs due to cancer mortality was started late and slowly comparing with other causes, and currently YLLs of death of cancer and ischemic heart disease were higher than those of stroke and diabetes in Japan. The increased trends of ischemic heart disease mortality in China between 1991 and 2009 comparing with Japanese populations reflected the lifestyle with higher dietary fat, higher blood lipids, and increased body weight.
In total, two articles were published in peer-reviewed journals, and five presentations were done in the international conferences. Several presentations for related epidemiological studies in the domestic conferences were conducted with supported by this grant.

Academic Significance and Societal Importance of the Research Achievements

人々の健康的なライフスタイルを維持することは、心血管疾患やがんの負担を減らすために非常に重要です。中国人人口のより高い食事性脂肪および太りすぎは虚血性心疾患の主な危険因子であり、そして2010年の負担は約20年前の日本の状況と同様でした。健康日本21(第二次)の目標を達成するために、全員が責任を持っています。

Report

(5 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (13 results)

All 2019 2018 2017 2016 2015

All Journal Article (2 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 2 results,  Open Access: 2 results) Presentation (10 results) (of which Int'l Joint Research: 5 results,  Invited: 1 results) Funded Workshop (1 results)

  • [Journal Article] Dietary Antioxidant Micronutrients and All-Cause Mortality: The Japan Collaborative Cohort Study for Evaluation of Cancer Risk2018

    • Author(s)
      Enbo Ma, Hiroyasu Iso, Kazumasa Yamagishi, Masahiko Ando, Kenji Wakai, and Akiko Tamakoshi
    • Journal Title

      Journal of Epidemiology

      Volume: 28 Issue: 9 Pages: 388-396

    • DOI

      10.2188/jea.JE20170023

    • NAID

      130007481554

    • ISSN
      0917-5040, 1349-9092
    • Year and Date
      2018-09-05
    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Mortality trends for ischemic heart disease in China: an analysis of 102 continuous disease surveillance points from 1991 to 20092018

    • Author(s)
      Wan X, Ren H, Ma E, Yang G
    • Journal Title

      BMC Public Health

      Volume: 18 Issue: 1 Pages: 52-52

    • DOI

      10.1186/s12889-017-4558-3

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] Changes of suicide rates in Fukushima and neighbor prefectures after the Great East Japan Earthquake.2019

    • Author(s)
      Ma E, Takahashi H.
    • Organizer
      The 29th Annual Scientific Meeting of the Japan Epidemiological Association. Tokyo
    • Related Report
      2018 Annual Research Report
  • [Presentation] Time trends of paternal mortality rates in 47 prefectures in Japan.2019

    • Author(s)
      Takahashi H, Ma E.
    • Organizer
      The 29th Annual Scientific Meeting of the Japan Epidemiological Association. Tokyo
    • Related Report
      2018 Annual Research Report
  • [Presentation] Stability of dietary pattern in Fukushima residents after the Great East Japan Earthquake: the Fukushima Health Management Survey 2011-2013.2019

    • Author(s)
      Ma E, Ohira T, Nakano H, Maeda M, Yasumura S, Kamiya K.
    • Organizer
      World Nutrition Conference 2019. Prague, Czech Republic.
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Changes of perinatal mortality between 2005 and 2015 in Japan - all country, Fukushima, and neighbour six prefetures.2018

    • Author(s)
      Takahashi H, Ma E.
    • Organizer
      The 28th Annual Scientific Meeting of the Japan Epidemiological Association., Japan.
    • Related Report
      2018 Annual Research Report
  • [Presentation] Changes of perinatal mortality between 2005 and 2015 in Japan - all country, Fukushima and neighbour six prefectures.2018

    • Author(s)
      Takahashi H, Ma E.
    • Organizer
      The 28th Annual Scientific Meeting of the Japan Epidemiological Association.
    • Related Report
      2017 Research-status Report
  • [Presentation] Trends of Years of Life Lost (YLL) due to leading chronic diseases in Japan, 1950-2014.2017

    • Author(s)
      Enbo Ma
    • Organizer
      The 21st International Epidemiological Association (IEA) World Congress of Epidemiology (WCE2017)
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Health promotion based on data: the MITO Health Community Study.2017

    • Author(s)
      Wagatsuma Y, Ma E.
    • Organizer
      The 76th Japanese Society of Public Health Conference.
    • Related Report
      2017 Research-status Report
  • [Presentation] Excessive Reactive Oxygen Species and the Gastric Cancer Risk: the JPHC Study.2016

    • Author(s)
      Ma E, Sasazuki S, Shimazu T, Sawada N, Yamagi T, Iwasaki M, Inoue M, Tsugane S
    • Organizer
      The BIT’s 9th World Cancer Congress 2016
    • Place of Presentation
      Shanghai, China
    • Year and Date
      2016-05-14
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Lifestyle-related factors and burden of cardiovascular diseases in Japan2016

    • Author(s)
      Enbo Ma
    • Organizer
      World Congress on Public Health and Nutrition
    • Place of Presentation
      Hotel Melia Avenida America, Madrid, Spain
    • Year and Date
      2016-03-10
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Declines of stroke mortality in Japan and China2015

    • Author(s)
      Enbo Ma
    • Organizer
      Association of Pacific Rim Universities Global Health Workshop
    • Place of Presentation
      Suita Campus, Osaka University, Osaka
    • Year and Date
      2015-10-30
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Funded Workshop] World Nutrition Conference 2019, Prague, Czech Republic.2019

    • Related Report
      2018 Annual Research Report

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Published: 2015-04-16   Modified: 2020-03-30  

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