Geriatric assessment is predicting the adverse events in treatment for the elder patients with cancer
| Project/Area Number |
15K08831
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Hygiene and public health
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| Research Institution | National Cancer Center Japan |
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Principal Investigator |
Ogawa Asao 国立研究開発法人国立がん研究センター, 先端医療開発センター, 分野長 (10466196)
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| Co-Investigator(Kenkyū-buntansha) |
木下 寛也 国立研究開発法人国立がん研究センター, 東病院, 医長 (30505897)
松本 禎久 国立研究開発法人国立がん研究センター, 東病院, 科長 (30544522)
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| Project Period (FY) |
2015-04-01 – 2019-03-31
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| Project Status |
Completed (Fiscal Year 2018)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 社会医学 / 衛生学・公衆衛生学 / 高齢者保健 / 介護福祉 / 社会科学 |
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| Outline of Final Research Achievements |
Comprehensive Geriatric Assessment is the gold standard for evaluating the global health status, and the diagnostic process focusing on determining an elderly person’s medical, psychosocial, and functional capability. In general, GA based support plans have been shown to improve overall survival, quality of life, and decrease the risk of hospitalization. On the other hand, it is unknown the usefulness of CGA in cancer treatment.
We developed easy to use a GA based assessment tool and evaluated the feasibility of this tool in cancer care setting. Frailty and cognitive impairment predicted the adverse events in cancer treatment.
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| Academic Significance and Societal Importance of the Research Achievements |
本研究の成果により、認知機能や生活機能の低下が、高齢者のがん治療が安全に実施できるかどうかに影響する事が明らかになった。このことにより、がん治療を開始する前に、今後治療が安全に実施できるかどうかを予め予測することが可能になる。
加えて、リスクがある事例に対しては、予めそのリスクを可能な限り下げるための取組みを行い、従来は難しかった治療を可能とする支持療法の開発につなげることができる。
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Report
(5 results)
Research Products
(143 results)
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[Journal Article] Prostaglandin D2 signaling mediated by the CRTH2 receptor is involved in MK-801-induced cognitive dysfunction.2016
Author(s)
Onaka Y, Shintani N, Nakazawa T, Kanoh T, Ago Y, Matsuda T, Hashimoto R, Ohi K, Hirai H, Nagata KY, Nakamura M, Kasai A, Hayata-Takano A, Nagayasu K, Takuma K, Ogawa A, Baba A, Hashimoto H.
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Journal Title
Behav Brain Res.
Volume: 314
Pages: 477-486
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] ぼちぼち2016
Author(s)
小川朝生
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Journal Title
緩和ケアー緩和ケアの魔法の言葉 どう声をかけたらいいかわからない時の道標
Volume: 26(Suppl.JUN)
Pages: 41-42
Related Report
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[Journal Article] Impact of depression on health utility value in cancer patients.2015
Author(s)
Fujisawa D, Inoguchi H, Shimoda H, Yoshiuchi K, Inoue S, Ogawa A, Okuyama T, Akechi T, Mimura M, Shimizu K, Uchitomi Y.
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Journal Title
Psycho-oncology
Volume: 25(5)
Issue: 5
Pages: 491-495
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Validation of the Japanese Version of Edmonton Symptom Assessment System-Revised.2015
Author(s)
Yokomichi N, Morita T, Nitto A, Takahashi N, Miyamoto S, Nishie H, Matsuoka J, Sakurai H, Ishihara T, Mori M, Trumi Y, Ogawa A
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Journal Title
Journal of Pain and Symptom Management
Volume: 50
Issue: 5
Pages: 718-23
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] The Association Between Depressive Symptoms and Age in Cancer Patients: A Multicenter Cross-Sectional Study.J Pain Symptom Manage.2015
Author(s)
Wada S, Shimizu K, Inoguchi H, Shimoda H, Yoshiuchi K, Akechi T, Uchida M, Ogawa A, Fujisawa D, Inoue S, Uchitomi Y, Matsushima E
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Journal Title
10.1016/j.jpainsymman.2015.07.011
Volume: 50
Issue: 6
Pages: 768-77
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Personality traits and coping styles explain anxiety in lung cancer patients to a greater extent than other factors.2015
Author(s)
Shimizu K, Nakaya N, Saito-Nakaya K, Akechi T, Ogawa A, Fujisawa D, Sone T, Yoshiuchi K, Goto K, Iwasaki M, Tsugane S, Uchitomi Y.
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Journal Title
Jpn J Clin Oncol
Volume: 45
Issue: 5
Pages: 456-63
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Establishing Cut-off Points for Defining Symptom Severity Using the Edmonton Symptom Assessment System-Revised Japanese Version2015
Author(s)
Yamaguchi T, Morita T, Nitto A, Takahashi N, Miyamoto S, Nishie H, Matsuoka J, Sakurai H, Ishihara T, Tarumi Y, Ogawa Asao
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Journal Title
Journal of Pain and Symptom Management
Volume: 51
Issue: 2
Pages: 292-7
DOI
Related Report
Peer Reviewed / Open Access
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[Presentation] せん妄の臨床2016
Author(s)
小川朝生
Organizer
日本精神神経学会学術総会
Place of Presentation
幕張メッセ（千葉県千葉市美浜区）
Year and Date
2016-06-02
Related Report
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[Presentation] 高齢者機能評価2015
Author(s)
小川朝生
Organizer
第２８回日本内視鏡外科学会総会
Place of Presentation
大阪市
Year and Date
2015-12-10
Related Report
Invited
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[Presentation] 不眠へのアプローチ2015
Author(s)
小川朝生
Organizer
第28回日本サイコオンコロジー学会総会
Place of Presentation
広島県広島市
Year and Date
2015-09-18
Related Report
Invited
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[Presentation] 認知症の緩和ケア2015
Author(s)
小川朝生
Organizer
第65回日本病院学会
Place of Presentation
長野県北佐久郡軽井沢町
Year and Date
2015-06-18
Related Report
Invited
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