Development of sensitive analytical method to analyze all synthetic cannabinoids
| Project/Area Number |
15K08834
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Hygiene and public health
|
|---|
| Research Institution | Osaka Institute of Public Health |
|---|
Principal Investigator |
Tagami Takaomi 地方独立行政法人 大阪健康安全基盤研究所, 衛生化学部, 主幹研究員 (00321943)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
武田 章弘 地方独立行政法人 大阪健康安全基盤研究所, 衛生化学部, 研究員 (00622755)
土井 崇広 地方独立行政法人 大阪健康安全基盤研究所, 衛生化学部, 主任研究員 (90516767)
淺田 安紀子 地方独立行政法人 大阪健康安全基盤研究所, 衛生化学部, 研究員 (80622753)
|
|---|
| Project Period (FY) |
2015-04-01 – 2019-03-31
|
| Project Status |
Completed (Fiscal Year 2018)
|
| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
|---|
| Keywords | 危険ドラッグ / 分析 |
|---|
| Outline of Final Research Achievements |
New psychoactive substances (NPS) have been found and identified in illicit drug products worldwide. Several NPS have been regulated as designated substances in Japan. Rapid, sensitive and reliable methods to analyze NPS in illicit drug products are needed. In this study, we developed two methods to distinguish positional isomers and a rapid analysis method for NPS in illicit drug products. These methods may be useful to analyze NPS in illicit drug products.
|
| Academic Significance and Societal Importance of the Research Achievements |
本研究では、位置異性体を識別する二つの分析法と危険ドラッグ中のNPSを迅速に分析する一つの分析法を確立した。位置異性体を識別する分析法を確立することにより、位置異性体を確実に同定することが可能となり、誤同定の防止が可能になることに加え、迅速な結果の確定が可能となる。また、迅速な分析法の確立は、言うまでもなく迅速な分析が可能となる。これらの分析法により「危険ドラッグの迅速な分析による流通阻止」による「事件、健康被害等の未然防止」が可能になると考えられる。
|
Report
(5 results)
Research Products
(19 results)
-
-
-
[Journal Article] Detection of pyrovalerone as a possible synthetic by-product of 4′-methyl-α-pyrrolidinohexanophenone and 4-methyl-α-ethylaminopentiophenone in illicit drug products2018
Author(s)
3)Tagami, T., Doi, T., Takeda, A., Asada, A., Kiyota, K., Sawabe, Y.
-
Journal Title
Forensic Toxicology
Volume: 印刷中
Issue: 2
Pages: 506-513
DOI
Related Report
Peer Reviewed
-
-
[Journal Article] Regioisomeric separation of ring-substituted cathinones by liquid chromatography-mass spectrometry with a naphthylethyl column.2017
Author(s)
Takeda, A., Tagami, T., Asada, A., Doi, T., Kawaguchi, M., Satsuki, Y., Sawabe, Y.
-
Journal Title
Forensic Toxicology
Volume: 印刷中
Issue: 2
Pages: 399-407
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
-
[Journal Article] Enantioseparation of the carboxamide-type synthetic cannabinoids N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide and methyl [1-(5-fluoropentyl)-1H-indazole-3-carbonyl]-valinate in illicit herbal products.2016
Author(s)
Doi, T., Asada, A., Takeda, A., Tagami, T., Katagi, M., Kamata, H., Sawabe,Y.
-
Journal Title
Journal of Chromatography A
Volume: 1473
Pages: 83-89
Related Report
Peer Reviewed / Acknowledgement Compliant
-
[Journal Article] Identification and characterization of α-PVT, α-PBT, and their bromothienyl analogs found in illicit drug products2016
Author(s)
Takahiro Doi, Akiko Asada, Akihiro Takeda, Takaomi Tagami, Munehiro Katagi,Shuntaro Matsuta, Hiroe Kamata, Masami Kawaguchi,Yuka Satsuki, Yoshiyuki Sawabe,Hirotaka Obana
-
Journal Title
Forensic Toxicol
Volume: 34
Issue: 1
Pages: 76-93
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
-
-
-
-
-
-
-
-
-
-
-
-
