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Effects of surface contamination on antibacterial activity of antibacterial metals

Research Project

Project/Area Number 15K08852
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical and hospital managemen
Research InstitutionOsaka City University

Principal Investigator

Kawakami Hiroshi  大阪市立大学, 大学院工学研究科, 准教授 (90305615)

Co-Investigator(Kenkyū-buntansha) 佐藤 嘉洋  大阪市立大学, 大学院工学研究科, 教授 (00170796)
Co-Investigator(Renkei-kenkyūsha) Wang Pengyuan  
KATO Hisashi  
KIKUCHI Yasushi  
SUZUKI Satoshi  
TAKASHIMA Yuta  
TODA Yuzo  
HIRAYAMA Kenta  
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords抗菌性金属材料 / 銅合金 / 表面汚損 / 院内感染対策 / 食中毒対策 / 抗菌性金属 / 銅 / ステンレス鋼 / 次亜塩素酸ナトリウム / 環境表面 / 院内感染管理 / 微生物制御 / 殺菌 / 殺菌消毒
Outline of Final Research Achievements

In this study, effects of i) surface contamination and ii) cleaning agents on antibacterial activities, and iii) effective cleaning methods for recovering the antibacterial activities of copper alloys, which were degraded by surface contamination, were studied. When the triolein contaminated surfaces were wiped clean with ethanol or 0.05 mass% sodium hypochlorite aq., the degraded antibacterial activities recovered to levels close to those with clean surfaces. For protein surface contamination, one cycle of wipe cleaning with sodium hypochlorite aq. did not result in complete recovery of degraded antibacterial activities. It is necessary to develop measure to prevent antibacterial metals from surface deterioration caused by cleaning agents.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (17 results)

All 2017 2016 2015

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Acknowledgement Compliant: 1 results) Presentation (15 results) (of which Int'l Joint Research: 2 results)

  • [Journal Article] 清拭に用いた薬剤が銅表面の抗菌性に及ぼす影響2017

    • Author(s)
      王鵬遠,川上洋司,佐藤嘉洋
    • Journal Title

      銅と銅合金

      Volume: 56 Pages: 323-328

    • NAID

      40021293652

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 清拭に用いた薬剤が銅表面の抗菌性に及ぼす影響2017

    • Author(s)
      王 鵬遠,川上洋司,佐藤嘉洋
    • Journal Title

      銅と銅合金

      Volume: 56

    • NAID

      40021293652

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] 清拭に用いた薬剤が銅表面の抗菌性に及ぼす影響2017

    • Author(s)
      王 鵬遠,川上洋司,佐藤嘉洋,菊地靖志
    • Organizer
      「バイオインターフェース先端マテリアルの創生」第 7 回シンポジウム
    • Place of Presentation
      大阪市立大学阿倍野キャンパス(大阪市阿倍野区旭町1-4-3)
    • Year and Date
      2017-02-10
    • Related Report
      2016 Research-status Report
  • [Presentation] タンパク質による表面汚損が銅合金の抗菌性に及ぼす影響2017

    • Author(s)
      戸田雄三,高嶋悠多 、川上洋司、佐藤嘉洋、菊地靖志
    • Organizer
      日本銅学会第57回講演大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 銅および銅合金の抗菌性に及ぼす表面粗さの影響2017

    • Author(s)
      加藤央士,佐藤嘉洋,川上洋司,菊地靖志
    • Organizer
      日本銅学会第57回講演大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 透過型電子顕微鏡による金属の抗菌作用の観察2017

    • Author(s)
      菊地靖志,高岡誠人,西岡裕貴,川上洋司,佐藤嘉洋
    • Organizer
      日本銅学会第57回講演大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 銅合金の抗菌性にタンパク質による表面汚損が及ぼす影響2017

    • Author(s)
      高嶋悠多 、戸田雄三、川上洋司、佐藤嘉洋、菊地靖志
    • Organizer
      日本防菌防黴学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 油脂汚損された銅含有ステンレス鋼の清拭後の抗菌性2017

    • Author(s)
      小林佑輔、平山堅太、川上洋司、佐藤嘉洋 、菊地靖志 、鈴木聡
    • Organizer
      日本防菌防黴学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Effects of surface stain and wiping using detergents on antibacterial activities of copper2017

    • Author(s)
      H. Kawakami, P. Wang, Y. Sato, Y. Kikuchi
    • Organizer
      4th International Conference on Prevention & Infection Control
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 拭き清掃に用いた薬剤が銅表面の抗菌性に及ぼす影響2016

    • Author(s)
      王 鵬遠,川上洋司,佐藤嘉洋,菊地靖志
    • Organizer
      日本銅学会第56回講演大会
    • Place of Presentation
      東海大学高輪キャンパス(東京都港区高輪2-3-23)
    • Year and Date
      2016-10-29
    • Related Report
      2016 Research-status Report
  • [Presentation] 油脂により汚損された銅合金表面の抗菌性に及ぼす拭き清掃の影響2016

    • Author(s)
      王 鵬遠,川上洋司,佐藤嘉洋,菊地靖志
    • Organizer
      日本防菌防黴学会第43回年次大会
    • Place of Presentation
      きゅりあん(東京都品川区東大井5-18-1)
    • Year and Date
      2016-09-26
    • Related Report
      2016 Research-status Report
  • [Presentation] 脂汚損された銅含有ステンレス鋼の拭き清掃後の抗菌性2016

    • Author(s)
      小林佑輔 、平山堅太 、川上洋司、佐藤嘉洋、菊地靖志、鈴木聡
    • Organizer
      日本防菌防黴学会第43回年次大会
    • Place of Presentation
      きゅりあん(東京都品川区東大井5-18-1)
    • Year and Date
      2016-09-26
    • Related Report
      2016 Research-status Report
  • [Presentation] Wipe Cleaning Method for Restoring Antibacterial Activities of Soiled Surfaces of an Antibacterial Stainless Steel2016

    • Author(s)
      H. Kawakami, K. Hirayama, Y. Sato, Y. Kikuchi
    • Organizer
      The ASM Microbe 2016
    • Place of Presentation
      Boston, USA
    • Year and Date
      2016-06-16
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] 表面汚損により低下した銅含有ステンレス鋼の抗菌性を回復させる洗浄剤の検討2016

    • Author(s)
      川上洋司,平山堅太,西久保秀行,鈴木聡,佐藤嘉洋,菊地靖志
    • Organizer
      「バイオインターフェース先端マテリアルの創生」第6回シンポジウム
    • Place of Presentation
      大阪市立大学(大阪市住吉区杉本3-3-138)
    • Year and Date
      2016-02-12
    • Related Report
      2015 Research-status Report
  • [Presentation] 銅含有ステンレス鋼表面の疎水性汚損に対する清掃と抗菌性2016

    • Author(s)
      平山堅太,川上洋司,佐藤嘉洋,菊地靖志,鈴木聡
    • Organizer
      「バイオインターフェース先端マテリアルの創生」第6回シンポジウム
    • Place of Presentation
      大阪市立大学(大阪市住吉区杉本3-3-138)
    • Year and Date
      2016-02-12
    • Related Report
      2015 Research-status Report
  • [Presentation] 銅含有ステンレス鋼表面の疎水性汚損と抗菌性2015

    • Author(s)
      平山堅太,川上洋司,佐藤嘉洋,菊地靖志,鈴木聡
    • Organizer
      日本鉄鋼協会 第170回秋季講演大会
    • Place of Presentation
      九州大学 伊都キャンパス(福岡市西区元岡744番地)
    • Year and Date
      2015-09-17
    • Related Report
      2015 Research-status Report
  • [Presentation] 銅含有ステンレス鋼表面の疎水性汚損と抗菌性2015

    • Author(s)
      平山堅太,川上洋司,佐藤嘉洋,菊地靖志,鈴木聡
    • Organizer
      日本防菌防黴学会 第42回 年次大会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府豊中市新千里東町1-4-2)
    • Year and Date
      2015-09-01
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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