| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Outline of Final Research Achievements |
In heatstroke, various organs can be damaged directly by heat exposure, and systemic inflammatory responses can also occur through the development of hypercytokinemia. The purpose of the present study was to elucidate how intake of an electrolyte drink before heat exposure modulates heat exposure-induced damage in a rat model. The results showed that mRNA relating with heat shock protein and cytokine was changed with heat exposure, and intake of an electrolyte drink prior to heat exposure suppressed the changes. These findings suggest that intake of an electrolyte drink before heat exposure reduces the intensity of heat stress to the body, thereby improving heat tolerance.
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