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Angiogenesis in skin wounds in rats

Research Project

Project/Area Number 15K08883
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Legal medicine
Research InstitutionTeikyo University

Principal Investigator

Nogami Makoto  帝京大学, 医学部, 教授 (20218291)

Co-Investigator(Renkei-kenkyūsha) ARAI TOMOMI  帝京大学, 医学部, 教務職員 (80570366)
TOUKAIRIN YOKO  帝京大学, 医学部, 教務職員 (90570367)
HOSHI TOMOAKI  帝京大学, 医学部, 教務職員 (70570365)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords時間遺伝子 / Per2 / 血管新生 / マウス / 皮膚創 / mRNA / リンパ管新生 / ラット / 皮膚 / 創 / mRNA
Outline of Final Research Achievements

Angiogenesis in the skin wound is important in forensic practice. Circadian rhythm of mRNA is known in the skin. In this study, we studied mRNA expressions of angiogenic factors in skin wounds by RTPCR method in circadian-rhythm defective per 2-deficient mice, and their control mice. Through this study, we have obtained novel findings that mRNA expressions of angiogenic factors are influenced by per 2 gene.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (1 results)

All 2017

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results)

  • [Journal Article] Circadian rhythms of angiogenic factors in skin and wound tissue in per 2-mutant mice2017

    • Author(s)
      Tomoaki Hoshi, Yoko Toukairin, Tomomi Arai, Makoto Nogami
    • Journal Title

      Biomedical Research and Clinical Practice

      Volume: 2 Issue: 2 Pages: 1-8

    • DOI

      10.15761/brcp.1000135

    • Related Report
      2017 Annual Research Report 2016 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant

URL: 

Published: 2015-04-16   Modified: 2019-03-29  

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