Determination of drug intake day by micro-segmental hair analysis
Project/Area Number |
15K08894
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Legal medicine
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Research Institution | National Research Institute of Police Science |
Principal Investigator |
Kuwayama Kenji 科学警察研究所, 法科学第三部, 主任研究官 (40356233)
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Co-Investigator(Kenkyū-buntansha) |
宮口 一 科学警察研究所, 法科学第三部, 室長 (10370884)
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Project Period (FY) |
2015-04-01 – 2020-03-31
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Project Status |
Completed (Fiscal Year 2019)
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Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2018: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
Keywords | 毛髪 / 薬物 / 質量分析 |
Outline of Final Research Achievements |
In this study, a method to detect drugs in 0.4-mm hair segments, corresponding to the hair growth length of a day, using liquid chromatography/tandem mass spectrometry (micro-segmental analysis) was developed. Moreover, the day of drug intake was determined using micro-segmental hair analysis based on ingestion of internal temporal markers before hair collection.
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Academic Significance and Societal Importance of the Research Achievements |
従来の毛髪中薬物の分画分析では、十分な検出感度を得るために数十本の毛髪を束ねた上で数cm間隔に分画するので、数か月単位での薬物摂取時期の推定しかできなかった。単毛髪のマイクロ分画分析の開発により、被疑者の供述、被害者の記憶等によらず科学的に日数単位での薬歴を把握でき、毛髪中薬物鑑定の証明力を向上させることができる。
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Report
(6 results)
Research Products
(32 results)
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[Presentation] Comparison between urine, blood, saliva, and fingerprints in forensic drug testing2015
Author(s)
Kenji Kuwayama, Hajime Miyaguchi, Tadashi Yamamuro, Kenji Tsujikawa, Tatsuyuki Kanamori, Yuko T. Iwata, Hiroyuki Inoue
Organizer
TIAFT meeting 2015
Place of Presentation
Florence, Italy
Year and Date
2015-08-30
Related Report
Int'l Joint Research
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