| Project/Area Number |
15K08903
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
General internal medicine(including psychosomatic medicine)
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| Research Institution | Meijo University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
菓子井 達彦 富山大学, 大学院医学薬学研究部(医学), 客員教授 (00313619)
梶浦 新也 富山大学, 大学院医学薬学研究部(医学), 助教 (70456383)
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| Research Collaborator |
IKEZAKI Tomoaki
NITTA Atsumi
MIWA Toshiro
HOSOKAWA Ayumu
YASUDA Hatsuna
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 倦怠感 / カルニチン / がん / 化学療法 / 支持療法 / 緩和医療 / シスプラチン / 緩和ケア / 尿細管障害 |
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| Outline of Final Research Achievements |
In this study, we examined observation to confirm quantitatively whether blood carnitine significantly decreased by the cisplatin dosage, and what carnitine leaked through the whole urine after the cisplatin dosage. This leakage changed parallel to a rise of the β2-microglobulin which was the marker of tubular impairment, we clarified that it was the leakage due to tubular impairment.
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