Fundamental research for treatment optimization in elderly patients with mesothelioma
| Project/Area Number |
15K08905
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
General internal medicine(including psychosomatic medicine)
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| Research Institution | Nagoya University |
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Principal Investigator |
MASAHIRO MORISE 名古屋大学, 医学部附属病院, 病院助教 (00612756)
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| Co-Investigator(Kenkyū-buntansha) |
近藤 征史 藤田保健衛生大学, 医学部, 教授 (00378077)
安藤 昌彦 名古屋大学, 医学部附属病院, 准教授 (10322736)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | 悪性胸膜中皮腫 / 高齢者 / 化学療法 / 消化器毒性 / 脆弱性 / 発熱性好中球減少症 / アウトカム予測 |
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| Outline of Final Research Achievements |
Chemotherapy induced nausea and vomitting (CINV) can be associated with discontinuation of cisplatin plus pemetrexed/carboplatin plus pemetrexed, which are standard regimen for advanced malignant mesothelioma. Based on our research, pemetrexed regimen showed higer indcidence of CINV compared to non-pemetrexed 3rd generation anticancer drugs.
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Report
(4 results)
Research Products
(9 results)
