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Measurement of gastrointestinal function using 3-D endoscope

Research Project

Project/Area Number 15K09057
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Gastroenterology
Research InstitutionOsaka University

Principal Investigator

Kenji Watabe  大阪大学, 医学部附属病院, 准教授 (50379244)

Co-Investigator(Kenkyū-buntansha) 辻井 正彦  大阪大学, 医学系研究科, 招へい教授 (40303937)
山田 憲嗣  大阪大学, 医学系研究科, 特任教授(常勤) (70364114)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords機能性消化管疾患 / 3D内視鏡 / 3次元内視鏡 / 計測 / 距離 / 容積 / コンプライアンス / 運動 / 蠕動波 / パノラマ
Outline of Final Research Achievements

The functional gastrointestinal disorders (FGID) are common in daily practice. Their pathophysiology includes impaired gastrointestinal motility and distention. World standard test for FGIDs requires specialized equipment and is rarely used in Japan. We previously developed technique of 3-D measurements using stereo endoscopy which mounted a compound eye system. Here, we examined its basic specification for measuring gastrointestinal function. Major findings are as follows. Stereo endoscope measured the movement of peristaltic wave which was set to 2 mm/s as 1.74 mm/s (13% error). Stereo endoscope measured the diameter of a cylinder which was built 20 mm in diameter as 19.6 mm (3% error) and the volume of a half-sphere which was built 20 mm in diameter as 1.9mm3 (theoretical value 2.09, 9% error). These findings demonstrate the potential of our stereo endoscopy to measure the gastrointestinal function precisely.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (7 results)

All 2017 2016 2015

All Journal Article (7 results) (of which Peer Reviewed: 6 results)

  • [Journal Article] 1)Evaluation of endoscopic entire 3D image acquisition of the digestive tract using a stereo endoscope.2017

    • Author(s)
      Watabe K (2nd)
    • Journal Title

      Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems.

      Volume: 10054 Pages: 1005412-1005412

    • Related Report
      2017 Annual Research Report
  • [Journal Article] Tissue drug concentrations of anti-tumor necrosis factor agents are associated with the long-term outcome of patients with Crohn's disease.2017

    • Author(s)
      Yoshihara T, Shinzaki S, Kawai S, Fujii H, Iwatani S, Yamaguchi T, Araki M, Hiyama S, Inoue T, Hayashi Y, Watabe K, Iijima H, Takehara T.
    • Journal Title

      Inflamm Bowel Dis.

      Volume: 23(12) Issue: 12 Pages: 2172-2179

    • DOI

      10.1097/mib.0000000000001260

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 臨床現場における睡眠時呼吸障害のスクリーニングのための非接触手法の検討2017

    • Author(s)
      Yutaka Matsuura, Hieyong Jeong, Kenji Yamada, Kenji Watabe and Yuko Ohno
    • Journal Title

      Journal of Robotics and Mechatronics

      Volume: 印刷中

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Evaluation of endoscopic entire 3D image acquisition of the digestive tract using a stereo endoscope2017

    • Author(s)
      Kayo Yoshimoto, Kenji Watabe, Tetsuji Fujinaga, Hideki Iijima, Masahiko Tsujii, Hideya Takahashi, Tetsuo Takehara, Kenji Yamada
    • Journal Title

      Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XV

      Volume: Proc. SPIE Pages: 10054-10054

    • DOI

      10.1117/12.2250774

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] p53 functional deficiency in human colon cancer cells promotes fibroblast-mediated angiogenesis and tumor growth.2016

    • Author(s)
      Hayashi Y, Tsujii M, Kodama T, Akasaka T, Kondo J, Hikita H, Inoue T, Tsujii Y, Maekawa A, Yoshii S, Shinzaki S, Watabe K, Tomita Y, Inoue M, Tatsumi T, Iijima H, Takehara T.
    • Journal Title

      Carcinogenesis.

      Volume: 37 Issue: 10 Pages: 972-984

    • DOI

      10.1093/carcin/bgw085

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] The effectiveness of an anti-human IL-6 receptor monoclonal antibody combined with chemotherapy to target colon cancer stem-like cells.2015

    • Author(s)
      Ying J, Tsujii M, Kondo J, Hayashi Y, Kato M, Akasaka T, Inoue T, Shiraishi E, Inoue T, Hiyama S, Tsujii Y, Maekawa A, Kawai S, Fujinaga T, Araki M, Shinzaki S, Watabe K, Nishida T, Iijima H, Takehara T.
    • Journal Title

      Int J Oncol.

      Volume: 46 Issue: 4 Pages: 1151-1159

    • DOI

      10.3892/ijo.2015.2851

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Integrated diagnostic strategy for the invasion depth of early gastric cancer by conventional endoscopy and EUS.2015

    • Author(s)
      sujii Y, Kato M, Inoue T, Yoshii S, Nagai K, Fujinaga T, Maekawa A, Hayashi Y, Akasaka T, Shinzaki S, Watabe K, Nishida T, Iijima H, Tsujii M, Takehara T.
    • Journal Title

      Gastrointest Endosc.

      Volume: 15 Issue: 3 Pages: 452-459

    • DOI

      10.1016/j.gie.2015.01.022

    • Related Report
      2015 Research-status Report
    • Peer Reviewed

URL: 

Published: 2015-04-16   Modified: 2019-03-29  

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