• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

A community-based epidemiological survey of the relationship between oral health and the presence of systemic diseases

Research Project

Project/Area Number 15K09071
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Cardiovascular medicine
Research InstitutionShinshu University

Principal Investigator

Izawa Atsushi  信州大学, 学術研究院保健学系, 教授 (50464095)

Co-Investigator(Kenkyū-buntansha) 池田 宇一  信州大学, 医学部, 特任教授 (30221063)
本郷 実  信州大学, 学術研究院保健学系, 教授 (40209317)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords歯周疾患 / 脳心血管疾患 / 心血管代謝性疾患 / 地域疫学データ / 脳心血管病 / 歯周病 / 残存歯数 / 心血管疾患 / 地域連携 / 予防 / 地域保健 / 特定健診 / 血圧 / 脂質 / 生活習慣病
Outline of Final Research Achievements

This study was aimed to examine relationships between oral health status and systemic diseases in a cohort of 6068 participants of periodontal screening in Matsumoto city between 2008 and 2015. Participants were recruited if they had at least one National Health Insurance claim (n=2574). The total number of lost teeth was significantly associated with the presence of myocardial infarction, angina pectoris, aneurysm, and hypertensive diseases. Interestingly, the presence of diabetes and diabetic vascular complications were significantly associated with the number of lost teeth. Moreover, the number of lost teeth was significantly associated with abnormal bone density and structure, bone fracture, and spine disorders. Similarly, the numbers of healthy teeth and remaining teeth were significantly associated with systemic diseases.
The number of lost teeth was significantly associated with the presence of atherosclerotic cardiovascular diseases, cardiometabolic and skeletal diseases.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (23 results)

All 2017 2016 2015 2014

All Journal Article (9 results) (of which Peer Reviewed: 8 results,  Open Access: 8 results) Presentation (13 results) (of which Int'l Joint Research: 6 results,  Invited: 2 results) Book (1 results)

  • [Journal Article] Study Project on Prevention of Metabolic Syndrome among Children, Adolescents, and Young Adults in Shinshu. Importance of cystatin C and uric acid levels in the association of cardiometabolic risk factors in Japanese junior high school students.2016

    • Author(s)
      Harada Mikiko, Izawa Atsushi, Hidaka Hiroya, Nakanishi Keisuke, Terasawa Fumiko, Motoki Hirohiko, Yazaki Yoshikazu, Ikeda Uichi, Hongo Minoru
    • Journal Title

      J Cardiol

      Volume: 69 Issue: 1 Pages: 222-227

    • DOI

      10.1016/j.jjcc.2016.03.013

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Early administration of tolvaptan preserves renal function in elderly patients with acute decompensated heart failure.2016

    • Author(s)
      Kimura K, Momose T, Hasegawa T, Morita T, Misawa T, Motoki H, Izawa A, Ikeda U.
    • Journal Title

      Journal of Cardiology

      Volume: 67 Issue: 5 Pages: 399-405

    • DOI

      10.1016/j.jjcc.2015.09.020

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Comparison of Inflammatory Biomarkers in Outpatients With Prior Myocardial Infarction2016

    • Author(s)
      Minamisawa M, Motoki H, Izawa A, Kashima Y, Hioki H, Abe N, Miura T, Ebisawa S, Miyashita Y, Koyama J, Ikeda U.
    • Journal Title

      International Heart Journal

      Volume: 57 Issue: 1 Pages: 11-17

    • DOI

      10.1536/ihj.15-197

    • NAID

      130005121001

    • ISSN
      1349-2365, 1349-3299
    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Predictive Value of Combining the Ankle-Brachial Index and SYNTAX Score for the Prediction of Outcome after Percutaneous Coronary Intervention (From the SHINANO Registry).2016

    • Author(s)
      Ueki Y, Miura T, Miyashita Y, Motoki H, Shimada K, Kobayashi M, Nakajima H, Kimura H, Akanuma H, Mawatari E, Sato T, Hotta S, Kamiyoshi Y, Maruyama T, Watanabe N, Eisawa T, Aso S, Uchikawa S, Hashizume N, Sekimura N, Morita T, Ebisawa S, Izawa A, Koyama J, Ikeda U.
    • Journal Title

      Am J Cardiol

      Volume: 117 Issue: 2 Pages: 179-185

    • DOI

      10.1016/j.amjcard.2015.10.042

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Clinical Impact of Rapid Reduction of Low-Density Lipoprotein Cholesterol Level on Long-Term Outcome of Acute Myocardial Infarction in the Statin Era: Subanalysis of the ALPS-AMI Study.2015

    • Author(s)
      Miura T, Izawa A, Motoki H, Miyashita Y, Kashima Y, Ebisawa S, Tomita T, Koyama J, Ikeda U.
    • Journal Title

      PLoS One

      Volume: 10 Issue: 6 Pages: e0127835-e0127835

    • DOI

      10.1371/journal.pone.0127835

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association between estimated glomerular filtration rate and peripheral arterial disease.2015

    • Author(s)
      Yamasaki S, Izawa A, Koshikawa M, Saigusa T, Ebisawa S, Miura T, Shiba Y, Tomita T, Miyashita Y, Koyama J, Ikeda U.
    • Journal Title

      Journal of Cardiology

      Volume: 66 Issue: 5 Pages: 430-434

    • DOI

      10.1016/j.jjcc.2015.01.011

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Prognostic Significance of Neuroadrenergic Dysfunction for Cardiovascular Events in Patients With Acute Myocardial Infarction2015

    • Author(s)
      Minamisawa M, Izawa A, Motoki H, Kashima Y, Hioki H, Abe N, Miura T, Ebisawa S, Miyashita Y, Koyama J, Ikeda U.
    • Journal Title

      Circulation Journal

      Volume: 79 Issue: 10 Pages: 2238-2245

    • DOI

      10.1253/circj.CJ-15-0265

    • NAID

      130005099848

    • ISSN
      1346-9843, 1347-4820
    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 急性冠症候群(ACS)を対象として長野県で実施された3つの大規模臨床研究で得られたこと.2015

    • Author(s)
      伊澤 淳,三浦 崇,海老澤聡一朗,嘉嶋勇一郎,岡田綾子,富田威,宮下裕介,小山 潤,池田宇一,大和眞史.
    • Journal Title

      長野県医学会雑誌

      Volume: 45 Pages: 35-35

    • Related Report
      2015 Research-status Report
  • [Journal Article] Assessment of Lipophilic vs. Hydrophilic Statin Therapy in Acute Myocardial Infarction2014

    • Author(s)
      Izawa A, Kashima Y, Miura T, Ebisawa S, Kitabayashi H, Yamamoto H, Sakurai S, Kagoshima M, Tomita T, Miyashita Y, Koyama J, Ikeda U.
    • Journal Title

      Circulation Journal

      Volume: 79 Issue: 1 Pages: 161-168

    • DOI

      10.1253/circj.CJ-14-0877

    • NAID

      130004704019

    • ISSN
      1346-9843, 1347-4820
    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] Characteristics of elderly patients with Heart Failure with Preserved Ejection Fraction: From CURE-HF Registry.2017

    • Author(s)
      Motoki H, Minamisawa M, Kimura K, Higuchi S, Yamasaki S, Izawa A, Kuwahara K.
    • Organizer
      第81回日本循環器学会学術集会
    • Place of Presentation
      金沢市,石川県立音楽堂ほか
    • Year and Date
      2017-03-17
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Clinical Profiles of Octogenarians with Heart Failure: From CURE-Heart Failure Registry.2017

    • Author(s)
      Motoki H, Minamisawa M, Kimura K, Higuchi S, Yamasaki S, Izawa A, Kuwahara K.
    • Organizer
      第81回日本循環器学会学術集会
    • Place of Presentation
      金沢市,石川県立音楽堂ほか
    • Year and Date
      2017-03-17
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] The Relationship between Hyperuricemia and Family History and Lifestyle in Japanese Junior High School Students.2017

    • Author(s)
      Harada M, Hongo M, Izawa A, Yazaki Y.
    • Organizer
      第81回日本循環器学会学術集会
    • Place of Presentation
      金沢市,石川県立音楽堂ほか
    • Year and Date
      2017-03-17
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Impact of periodontitis and tooth loss on the association of systemic atherosclerosis: a cohort study based on the National Health Insurance receipts.2017

    • Author(s)
      Atsushi Izawa, Jun-ichi Suzuki, Takashi Sugiyama, Hiroki Ogawa, Masashi Takeda, Jun-ichiro Yamagishi, Satoshi Takebuchi, Tatsuto Ohkubo, Hitoshi Kuneshita, Yoshihiro Inoue, Takeshi Yokoyama, and Atsushi Sugiyama.
    • Organizer
      第49回日本動脈硬化学会総会・学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 歯周疾患と心血管疾患の関連:歯周疾患健診と診療報酬明細に基づく疫学調査-医科歯科連携による先進予防医療研究会・松本の活動.2017

    • Author(s)
      伊澤淳、鈴木淳一、杉山貴、小川浩樹、武田正、山岸淳一郎、竹淵哲、大久保達人、久根下斉、井上好弘、横山猛嗣、杉山敦
    • Organizer
      第65回日本心臓病学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 残存歯数と心血管代謝危険因子の関連:医科歯科連携による先進予防医療研究会・松本による疫学調査.2017

    • Author(s)
      7.伊澤淳、鈴木淳一、杉山貴、小川浩樹、武田正、山岸淳一郎、竹淵哲、大久保達人、久根下斉、井上好弘、横山猛嗣、杉山敦
    • Organizer
      第65回日本心臓病学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 歯周疾患と心血管代謝疾患との関連:診療報酬明細に基づく疫学調査. Association between Periodontal Disease and Cardiometabolic Diseases: a Cohort Study Based on the National Health Insurance Receipts.2017

    • Author(s)
      伊澤淳
    • Organizer
      第40回日本高血圧学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 歯周疾患と全身疾患の関連~歯科医科連携によるOral-systemic connectionの展望~.2017

    • Author(s)
      伊澤淳
    • Organizer
      日本歯周病学会60周年記念京都大会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 歯周病と全身疾患の関連(Oral-systemic connection):松本市における歯科医科連携と展望.2017

    • Author(s)
      伊澤淳
    • Organizer
      日本歯周病学会60周年記念京都大会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] A 2-year follow-up of proprotein convertase subtilisin/kexin type 9 levels in patients with myocardial infarction: A subanalysis of the ALPS-AMI study.2015

    • Author(s)
      Kashima Y, Izawa A, Imamura H, Ikeda U.
    • Organizer
      American Heart Association
    • Place of Presentation
      Orlando (USA)
    • Year and Date
      2015-11-07
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 心室中隔基部の菲薄化を認めた抗ミトコンドリアM2抗体陽性筋炎の1例.2015

    • Author(s)
      伊澤 淳、石井 亘、植田初江、高橋 済、木村和広、樋口智子、南澤匡俊、竹内崇博、元木博彦、岡田綾子、小山 潤、池田宇一.
    • Organizer
      第35回日本サルコイドーシス/肉芽腫性疾患学会総会.
    • Place of Presentation
      ホテルエルセラーン大阪(大阪)
    • Year and Date
      2015-11-07
    • Related Report
      2015 Research-status Report
  • [Presentation] Comparison of usefulness of coronary SYNTAX score in patients with prior heart failure with preserved ejection fraction versus with reduced ejection fraction: a sub-analysis of shinano registry.2015

    • Author(s)
      Minamisawa M, Miura T, Motoki H, Hioki H, Hashizume N, Abe N, Ebisawa S, Izawa A, Koyama J, Ikeda U.
    • Organizer
      ESC2015(欧州心臓学会議)
    • Place of Presentation
      London (UK)
    • Year and Date
      2015-08-29
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Diagnostic significance of duration of myocardial early systolic lengthening in patients with stable coronary artery disease.2015

    • Author(s)
      Minamisawa M, Koyama J, Miura T, Saigusa T, Ebisawa S, Motoki H, Okada A, Izawa A, Ikeda U.
    • Organizer
      ESC2015(欧州心臓学会議)
    • Place of Presentation
      London (UK)
    • Year and Date
      2015-08-29
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Book] 「急性大動脈解離」循環器疾患最新の治療 2016-2017.堀 正二、永井良三、伊藤 浩:編集2016

    • Author(s)
      伊澤 淳、池田宇一(分担執筆)
    • Total Pages
      626
    • Publisher
      南江堂
    • Related Report
      2016 Research-status Report

URL: 

Published: 2015-04-16   Modified: 2019-03-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi