A community-based epidemiological survey of the relationship between oral health and the presence of systemic diseases
Project/Area Number |
15K09071
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Cardiovascular medicine
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Research Institution | Shinshu University |
Principal Investigator |
Izawa Atsushi 信州大学, 学術研究院保健学系, 教授 (50464095)
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Co-Investigator(Kenkyū-buntansha) |
池田 宇一 信州大学, 医学部, 特任教授 (30221063)
本郷 実 信州大学, 学術研究院保健学系, 教授 (40209317)
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Project Period (FY) |
2015-04-01 – 2018-03-31
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Project Status |
Completed (Fiscal Year 2017)
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Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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Keywords | 歯周疾患 / 脳心血管疾患 / 心血管代謝性疾患 / 地域疫学データ / 脳心血管病 / 歯周病 / 残存歯数 / 心血管疾患 / 地域連携 / 予防 / 地域保健 / 特定健診 / 血圧 / 脂質 / 生活習慣病 |
Outline of Final Research Achievements |
This study was aimed to examine relationships between oral health status and systemic diseases in a cohort of 6068 participants of periodontal screening in Matsumoto city between 2008 and 2015. Participants were recruited if they had at least one National Health Insurance claim (n=2574). The total number of lost teeth was significantly associated with the presence of myocardial infarction, angina pectoris, aneurysm, and hypertensive diseases. Interestingly, the presence of diabetes and diabetic vascular complications were significantly associated with the number of lost teeth. Moreover, the number of lost teeth was significantly associated with abnormal bone density and structure, bone fracture, and spine disorders. Similarly, the numbers of healthy teeth and remaining teeth were significantly associated with systemic diseases. The number of lost teeth was significantly associated with the presence of atherosclerotic cardiovascular diseases, cardiometabolic and skeletal diseases.
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Report
(4 results)
Research Products
(23 results)
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[Journal Article] Study Project on Prevention of Metabolic Syndrome among Children, Adolescents, and Young Adults in Shinshu. Importance of cystatin C and uric acid levels in the association of cardiometabolic risk factors in Japanese junior high school students.2016
Author(s)
Harada Mikiko, Izawa Atsushi, Hidaka Hiroya, Nakanishi Keisuke, Terasawa Fumiko, Motoki Hirohiko, Yazaki Yoshikazu, Ikeda Uichi, Hongo Minoru
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Journal Title
J Cardiol
Volume: 69
Issue: 1
Pages: 222-227
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Comparison of Inflammatory Biomarkers in Outpatients With Prior Myocardial Infarction2016
Author(s)
Minamisawa M, Motoki H, Izawa A, Kashima Y, Hioki H, Abe N, Miura T, Ebisawa S, Miyashita Y, Koyama J, Ikeda U.
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Journal Title
International Heart Journal
Volume: 57
Issue: 1
Pages: 11-17
DOI
NAID
ISSN
1349-2365, 1349-3299
Related Report
Peer Reviewed / Open Access
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[Journal Article] Predictive Value of Combining the Ankle-Brachial Index and SYNTAX Score for the Prediction of Outcome after Percutaneous Coronary Intervention (From the SHINANO Registry).2016
Author(s)
Ueki Y, Miura T, Miyashita Y, Motoki H, Shimada K, Kobayashi M, Nakajima H, Kimura H, Akanuma H, Mawatari E, Sato T, Hotta S, Kamiyoshi Y, Maruyama T, Watanabe N, Eisawa T, Aso S, Uchikawa S, Hashizume N, Sekimura N, Morita T, Ebisawa S, Izawa A, Koyama J, Ikeda U.
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Journal Title
Am J Cardiol
Volume: 117
Issue: 2
Pages: 179-185
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Association between estimated glomerular filtration rate and peripheral arterial disease.2015
Author(s)
Yamasaki S, Izawa A, Koshikawa M, Saigusa T, Ebisawa S, Miura T, Shiba Y, Tomita T, Miyashita Y, Koyama J, Ikeda U.
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Journal Title
Journal of Cardiology
Volume: 66
Issue: 5
Pages: 430-434
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Prognostic Significance of Neuroadrenergic Dysfunction for Cardiovascular Events in Patients With Acute Myocardial Infarction2015
Author(s)
Minamisawa M, Izawa A, Motoki H, Kashima Y, Hioki H, Abe N, Miura T, Ebisawa S, Miyashita Y, Koyama J, Ikeda U.
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Journal Title
Circulation Journal
Volume: 79
Issue: 10
Pages: 2238-2245
DOI
NAID
ISSN
1346-9843, 1347-4820
Related Report
Peer Reviewed / Open Access
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[Journal Article] Assessment of Lipophilic vs. Hydrophilic Statin Therapy in Acute Myocardial Infarction2014
Author(s)
Izawa A, Kashima Y, Miura T, Ebisawa S, Kitabayashi H, Yamamoto H, Sakurai S, Kagoshima M, Tomita T, Miyashita Y, Koyama J, Ikeda U.
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Journal Title
Circulation Journal
Volume: 79
Issue: 1
Pages: 161-168
DOI
NAID
ISSN
1346-9843, 1347-4820
Related Report
Peer Reviewed / Open Access
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[Presentation] Impact of periodontitis and tooth loss on the association of systemic atherosclerosis: a cohort study based on the National Health Insurance receipts.2017
Author(s)
Atsushi Izawa, Jun-ichi Suzuki, Takashi Sugiyama, Hiroki Ogawa, Masashi Takeda, Jun-ichiro Yamagishi, Satoshi Takebuchi, Tatsuto Ohkubo, Hitoshi Kuneshita, Yoshihiro Inoue, Takeshi Yokoyama, and Atsushi Sugiyama.
Organizer
第49回日本動脈硬化学会総会・学術集会
Related Report
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