Risk prediction for sudden cardiac death by quantitative analysis of fragmented QRS and J wave using differentiation of signal addition

• Project/Area Number: 15K09082
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Cardiovascular medicine
• Research Institution: Okayama University
• Principal Investigator: Morita Hiroshi 岡山大学, 医歯薬学総合研究科, 教授 (50322227)
• Co-Investigator(Kenkyū-buntansha): 杉山 洋樹 岡山大学, 医学部, 客員研究員 (20726137)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000); Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: 心臓性突然死 / 致死的不整脈 / 遺伝性不整脈 / QRS棘波 / 早期再分極 / J波 / fragmented QRS / 心室細動 / 突然死 / 分裂性QRS波 / 心臓突然死 / Brugada症候群 / J波症候群 / QT延長症候群 / J波(早期再分極)

Outline of Final Research Achievements

Fragmented QRS (fQRS) represents intraventricular conduction abnormality due to myocardial injury and fibrosis. fQRS will result in arrhythmogeneic substrate and cardiac dysfuncitn. J wave is also electrophysiological abnormality that can promote lethal arrhythmias. We have evaluated existence of fQRS and J wave in various heart diseases. Our published data were adopted for “J-wave syndromes expert consensus conference report” endorsed by APHRS, EHRA, HRS and SOLAECE and “Guidelines for diagnosis and management of inherited arrhythmias; JCS 2017” by Japanese Circulation Society.

Research Products

• [Journal Article] Identification of electrocardiographic risk markers for the initial and recurrent episodes of ventricular fibrillation in patients with Brugada syndrome. (2018)
  • Author(s): Morita H, Watanabe A, Kawada S, Miyamoto M, Morimoto Y, Nakagawa K, Nishii N, Nakamura K, Ito H.
  • Journal Title: J Cardiovasc Electrophysiol Volume: 29 Issue: 1 Pages: 107-114
  • DOI: 10.1111/jce.13349
  • Peer Reviewed
• [Journal Article] Impact of premature activation of the right ventricle with programmed stimulation in Brugada syndrome. (2018)
  • Author(s): Nakagawa K, Nagase S, Morita H, Wada T, Tanaka M, Murakami M, Watanabe A, Nishii N, Nakamura K, Kusano KF, Ito H, Ohe T.
  • Journal Title: J Cardiovasc Electrophysiol Volume: 29 Issue: 1 Pages: 71-78
  • DOI: 10.1111/jce.13336
  • Peer Reviewed
• [Journal Article] Analysis of arrhythmic events is useful to detect lead failure earlier in patients followed by remote monitoring. (2018)
  • Author(s): Nishii N, Miyoshi A, Kubo M, Miyamoto M, Morimoto Y, Kawada S, Nakagawa K, Watanabe A, Nakamura K, Morita H, Ito H.
  • Journal Title: J Cardiovasc Electrophysiol. Volume: 29 Issue: 3 Pages: 463-470
  • DOI: 10.1111/jce.13399
  • Peer Reviewed
• [Journal Article] Different responses to exercise between Andersen?Tawil syndrome and catecholaminergic polymorphic ventricular tachycardia (2017)
  • Author(s): Inoue Yuko Y、Aiba Takeshi、Kawata Hiro、Sakaguchi Tomoko、Mitsuma Wataru、Morita Hiroshi、Noda Takashi、Takaki Hiroshi、Toyohara Keiko、Kanaya Yoshiaki、Itoi Toshiyuki、Mitsuhashi Takeshi、Sumitomo Naokata、Cho Yongkeun、Yasuda Satoshi、Kamakura Shiro、Kusano Kengo、Miyamoto Yoshihiro、Horie Minoru、Shimizu Wataru
  • Journal Title: Europace Volume: 印刷中 Issue: 10 Pages: 1675-1682
  • DOI: 10.1093/europace/eux351
  • Peer Reviewed / Open Access
• [Journal Article] Genotype-phenotype correlation of SCN5A mutation for clinical and electrocardiographic characteristics of probands with Brugada syndrome: Japanese Multicenter Registry. (2017)
  • Author(s): Yamagata K, Horie M, et al.
  • Journal Title: Circulation Volume: 印刷中 Issue: 23 Pages: 0-0
  • DOI: 10.1161/circulationaha.117.027983
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Distribution and Prognostic Significance of Fragmented QRS in Patients with Brugada Syndrome. (2017)
  • Author(s): Morita H, Watanabe A, Morimoto Y, Kawada S, Tachibana M, Nakagawa K, Nishii N, Ito H.
  • Journal Title: Circ Arrhythm Electrophysiol Volume: 印刷中 Issue: 3
  • DOI: 10.1161/circep.116.004765
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Exercise stress test reveals ineligibility for subcutaneous implantable cardioverter defibrillator in patients with Brugada syndrome. (2017)
  • Author(s): Tachibana M, Nishii N, Morita H, Nakagawa K, Watanabe A, Nakamura K, Ito H
  • Journal Title: J Cardiovasc Electrophysiol Volume: 28 Issue: 12 Pages: 1454-1459
  • DOI: 10.1111/jce.13315
  • Peer Reviewed
• [Journal Article] Comparison of longevity and clinical outcomes of implantable cardioverter-defibrillator leads among manufacturers. (2017)
  • Author(s): Kawada S, Nishii N, Morimoto Y, Miyoshi A, Tachibana M, Sugiyama H, Nakagawa K, Watanabe A, Morita H, Ito H.
  • Journal Title: Heart Rhythm Volume: 14 Issue: 10 Pages: 1469-1503
  • DOI: 10.1016/j.hrthm.2017.05.020
  • Peer Reviewed
• [Journal Article] Local Left Ventricular Epicardial J Waves and Late Potentials in Brugada Syndrome Patients with Inferolateral Early Repolarization Pattern. (2017)
  • Author(s): Ueoka A, Morita H, Watanabe A, Nakagawa K, Nishii N, Nagase S, Ohe T, Ito H
  • Journal Title: Front Physiol. Volume: 8 Pages: 14-14
  • DOI: 10.3389/fphys.2017.00014
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Complete right bundle branch block and QRS-T discordance can be the initial clue to detect S-ICD ineligibility. (2017)
  • Author(s): Tachibana M, Nishii N, Morimoto Y, Kawada S, Miyoshi A, Sugiyama H, Nakagawa K, Watanabe A, Nakamura K,Morita H, Ito H.
  • Journal Title: Journal of Cardiology Volume: 印刷中 Issue: 1 Pages: 23-28
  • DOI: 10.1016/j.jjcc.2016.11.014
  • NAID: 120006486862
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Prognostic significance of fever-induced Brugada syndrome. (2016)
  • Author(s): Mizusawa Y, Morita H, Adler A, Havakuk O, Thollet A, Maury P, Wang DW, Hong K, Gandjbakhch E, Sacher F, Hu D, Amin AS, Lahrouchi N, Tan HL, Antzelevitch C, Probst V, Viskin S, Wilde AA.
  • Journal Title: Heart Rhythm Volume: 13 Issue: 7 Pages: 1515-1520
  • DOI: 10.1016/j.hrthm.2016.03.044
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge: Endorsed by the Asia Pacific Heart Rhythm Society (APHRS), the European Heart Rhythm Association (EHRA), the Heart Rhythm Society (HRS), and the Latin American Society of Cardiac Pacing and Electrophysiology (Sociedad Latinoamericana de Estimulacifin Cardiaca y Electrofsiologia [SOLAECE]). (2016)
  • Author(s): Antzelevitch C, Horie M, et al.
  • Journal Title: Europace Volume: 13 Pages: 315-339
  • DOI: 10.1093/europace/euw235
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Activation Pattern of the Polymorphic Ventricular Tachycardia and Ventricular Fibrillation on Body Surface Mapping in Patients With Brugada Syndrome (2016)
  • Author(s): Ueoka A, Morita H, Watanabe A, Nakagawa K, Nishii N, Nagase S, Ohe T, Ito H.
  • Journal Title: Circulation Journal Volume: 80 Issue: 8 Pages: 1734-1743
  • DOI: 10.1253/circj.CJ-16-0124
  • NAID: 130005166108
  • ISSN: 1346-9843, 1347-4820
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge. (2016)
  • Author(s): Antzelevitch C, Yan GX, Ackerman MJ, Borggrefe M, Corrado D, Guo J, Gussak I, Hasdemir C, Horie M, Huikuri H, Ma C, Morita H, Nam GB, Sacher F, Shimizu W, Viskin S, Wilde AA.
  • Journal Title: Heart Rhythm Volume: 13
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge. (2016)
  • Author(s): Antzelevitch C, Yan GX, Ackerman MJ, Borggrefe M, Corrado D, Guo J, Gussak I, Hasdemir C, Horie M, Huikuri H, Ma C, Morita H, Nam GB, Sacher F, Shimizu W, Viskin S, Wilde AA.
  • Journal Title: Journal of Arrhythmia Volume: 32 Pages: 315-339
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] J波症候群 (2016)
  • Author(s): 森田 宏
  • Journal Title: 医学の歩み Volume: 256 Pages: 668-674
• [Journal Article] Brugada症候群をどう診断するか (2016)
  • Author(s): 森田 宏
  • Journal Title: Heart View Volume: 20 Pages: 20-27
• [Journal Article] Brugada症候群・J波症候群 (2016)
  • Author(s): 上岡 亮、森田 宏
  • Journal Title: 臨床と研究 Volume: 93 Pages: 117-121
• [Journal Article] Incidence and Clinical Significance of Brugada Syndrome Masked by Complete Right Bundle-Branch Block (2015)
  • Author(s): Wada T, Nagase S, Morita H, Nakagawa K, Nishii N, Nakamura K, Kohno K, Ito H, Kusano KF, Ohe T.
  • Journal Title: Circulation Journal Volume: 79 Issue: 12 Pages: 2568-2575
  • DOI: 10.1253/circj.CJ-15-0618
  • NAID: 130005110922
  • ISSN: 1346-9843, 1347-4820
  • Peer Reviewed / Open Access
• [Journal Article] Risk Stratification in Patients With Brugada Syndrome Without Previous Cardiac Arrest (2015)
  • Author(s): Okamura H, Kamakura T, Morita H, Tokioka K, Nakajima I, Wada M, Ishibashi K, Miyamoto K, Noda T, Aiba T, Nishii N, Nagase S, Shimizu W, Yasuda S, Ogawa H, Kamakura S, Ito H, Ohe T, Kusano KF
  • Journal Title: Circulation Journal Volume: 79 Issue: 2 Pages: 310-317
  • DOI: 10.1253/circj.CJ-14-1059
  • NAID: 130004704033
  • ISSN: 1346-9843, 1347-4820
  • Peer Reviewed / Open Access
• [Presentation] Shanghai Score System and Risk Stratification of Brugada and J Wave Syndromes (2017)
  • Author(s): Morita H, Kawada S, Watanabe A, Morimoto Y, Tachibana M, Nakagawa K, Nishii N, Ito H
  • Organizer: 81th Annual Scientific Meeting of the Japanese Circulation Society
  • Place of Presentation: 石川県立音楽堂（石川県金沢市）
  • Year and Date: 2017-03-17
  • Int'l Joint Research / Invited
• [Presentation] Prognostic Significance of the Shanghai Score System for Diagnosis of Brugada Syndrome (2017)
  • Author(s): Kawada S, Morita H, Watanabe A, Morimoto Y, Tachibana M, Nakagawa K, Nishii N, Ito H
  • Organizer: 81th Annual Scientific Meeting of the Japanese Circulation Society
  • Place of Presentation: 石川県立音楽堂（石川県金沢市）
  • Year and Date: 2017-03-17
  • Int'l Joint Research
• [Presentation] Factors for Ineligibility of Candidates for Subcutaneous Implantable Defbrillator in Patients with Brugada Syndrome (2017)
  • Author(s): Tachibana M, Nishii N, Morimoto Y, Kawada S, Miyoshi A, Sugiyama H, Nakagawa K, Watanabe A, Nakamura K, Morita H, Ito H
  • Organizer: 81th Annual Scientific Meeting of the Japanese Circulation Society
  • Place of Presentation: 石川県立音楽堂（石川県金沢市）
  • Year and Date: 2017-03-17
  • Int'l Joint Research
• [Presentation] Biological Pacemaker Created by HCN4-overexpressing Human iPS Cell-derived Cardiomyocytes (2017)
  • Author(s): Nakamura K, Saito Y, Yoshida M, Watanabe A, Nishii N, Morita H, Ito H
  • Organizer: 81th Annual Scientific Meeting of the Japanese Circulation Society
  • Place of Presentation: 石川県立音楽堂（石川県金沢市）
  • Year and Date: 2017-03-17
  • Int'l Joint Research
• [Presentation] Mutation Spot-sensitive Clinical Features and Risk of Life-threatening Arrhythmia in Long QT Syndrome Type 1 in Japan (2017)
  • Author(s): Kashiwa A, Aiba T, Makimoto H, Yagihara N, Watanabe H, Ohno S, Hayashi K, Sumitomot N, Yoshinaga M, Morita H, Minamoto Y, Makita N, Horie M, Yasuda S, Kusano K, Shimizu W.
  • Organizer: 81th Annual Scientific Meeting of the Japanese Circulation Society
  • Place of Presentation: 石川県立音楽堂（石川県金沢市）
  • Year and Date: 2017-03-17
  • Int'l Joint Research
• [Presentation] Genotype-Phenotype Correlation of SCN5A Mutations for the Clinical and Electrocardiographic Characteristics of Probands with Brugada Syndrome: A Japanese Multicenter Registry (2017)
  • Author(s): Yamagata K, Horie M, Alba T, Ogawa S, Aiszawa Y, Ohe T, Yamagishi M, Makita N, Sakurada H, Tanaka T, Shimizu A, Hagiwara N, Kishi R, Nakano Y, Takagi M, Makiyama T, Ohno S, Fukuda K, Watanabe H, Morita H, Hayashi K, Gusano K, Kamakura S, Pasuda S, Ogawa H, Miyamaoto Y, Kapplinger JD, AckermN MJ, Shimizu W.
  • Organizer: 81th Annual Scientific Meeting of the Japanese Circulation Society
  • Place of Presentation: 石川県立音楽堂（石川県金沢市）
  • Year and Date: 2017-03-17
  • Int'l Joint Research
• [Presentation] Late R' Wave Axis of Complete Right Bundle Branch Block Represents Conduction Disturbance within Right Ventricle in Brugada Syndrome (2017)
  • Author(s): 森本芳正、森田 宏、川田哲史、橘 元見、中川晃志、渡邊敦之、西井伸洋、中村一文、伊藤浩
  • Organizer: 81th Annual Scientific Meeting of the Japanese Circulation Society
  • Place of Presentation: 石川県立音楽堂（石川県金沢市）
  • Year and Date: 2017-03-17
  • Int'l Joint Research
• [Presentation] Significance of the distribution of fragmented QRS in Patients with Brugada Syndrome. (2017)
  • Author(s): Morita H, Watanabe A, Ueoka A, Tachibana M, Tsushima S, Nakagawa K, Nishii N, Ito H.
  • Organizer: Heart Rhythm 2017
  • Int'l Joint Research / Invited
• [Presentation] Risk Stratification in Brugada Syndrome (Invited Symposium 5) (2017)
  • Author(s): Morita H
  • Organizer: Asian Pasific Heart Rhythm Society 2017
  • Int'l Joint Research / Invited
• [Presentation] Depolarization Abnormality in High Risk Patients with Brugada Syndrome (Invited Symposium) (2017)
  • Author(s): Morita H
  • Organizer: Asian Pacific Heart Rhythm Society 2017
  • Int'l Joint Research / Invited
• [Presentation] Ten reasons why you cannot believe the repolarization / depolarization hypotheses. Symposium 7. Mechanisms Underlying Brugada Syndrome (2016)
  • Author(s): Morita H, Watanabe A, Tachibana M, Nakagawa K, Nishii N, Ito H.
  • Organizer: Annual Meeting of the Japanese Heart Rhythm Society 2016
  • Place of Presentation: 札幌コンベンションセンター（北海道札幌市）
  • Year and Date: 2016-07-14
  • Int'l Joint Research / Invited
• [Presentation] Symposium 32. Catheter Ablation for Brugada Syndrome: Should We Target the Trigger or the Substrate of Ventricular Fibrillation? (2016)
  • Author(s): Watanabe A, Morita H, Ito H.
  • Organizer: Annual Meeting of the Japanese Heart Rhythm Society 2016
  • Place of Presentation: 札幌コンベンションセンター（北海道札幌市）
  • Year and Date: 2016-07-14
  • Int'l Joint Research
• [Presentation] APHRS-EHRS Joint Session.: Asymptomatic Brugada Syndrome. (2016)
  • Author(s): Morita H
  • Organizer: Cardiostim 2016
  • Place of Presentation: Nice Acropolis Convention Center(ニース、フランス）
  • Year and Date: 2016-06-08
  • Int'l Joint Research / Invited
• [Presentation] Prognostic Significance of the distribution of fragmented QRS in Patients with Brugada Syndrome (2016)
  • Author(s): Hiroshi Morita, Atsuyuki Watanabe, Akira Ueoka, Motomi Tachibana, Syo Tsushima, Koji Nakagawa, Nobuhiro Nishii, Hiroshi Ito
  • Organizer: Heart Rhythm 2016
  • Place of Presentation: Moscone Center(サンフランシスコ、アメリカ合衆国)
  • Year and Date: 2016-05-04
  • Int'l Joint Research
• [Presentation] Prognostic value of early repolarization pattern in development of ventricular fibrillation in accidental hypothermia. (2015)
  • Author(s): Morita H.
  • Organizer: Asian Pacific Heart Rhythm Society Scientific Sessions 2015.
  • Place of Presentation: Melbourne Convention and Exbibition Centre(メルボルン オーストラリア).
  • Year and Date: 2015-11-19
  • Invited
• [Presentation] Early repolarisation and risk of ventricular arrhythmia. (2015)
  • Author(s): Morita H, Sugiyama H, Nakagawa K, Nishii N, Watanabe A, Ito H.
  • Organizer: Asian Pacific Heart Rhythm Society Scientific Sessions 2015.
  • Place of Presentation: Melbourne Convention and Exbibition Centre(メルボルン オーストラリア).
  • Year and Date: 2015-11-19
  • Invited
• [Presentation] Occurrence of arrhythmias during heart failure detected by remote monitoring system of implantable cardiac devices. (2015)
  • Author(s): Morita H, Nishii N, Nakamura K, Ito H.
  • Organizer: 第19回日本心不全学会学術集会
  • Place of Presentation: グランフロント大阪（大阪府大阪市）
  • Year and Date: 2015-10-22
  • Invited
• [Presentation] Circadian Variation, rate-dependent dynamics of late potnential (LP) in sarcoidosis, ARVC, IVF, Brugada syndrome evaluated by SAECG using 24h-Holter ECG. (2015)
  • Author(s): Sangawa M, Morita H, Tachibana M, Nakagawa K, Nishii N, Nagase S, Nakamura K, Ito H.
  • Organizer: 第30回日本不整脈学会学術大会・第32回日本心電学会学術集会 合同学術大会
  • Place of Presentation: 国立京都国際会議場（京都府京都市）
  • Year and Date: 2015-07-29
• [Presentation] New risk stratification tool in patietns with Brugada syndrome. –Prognositic significance of pilsicainide-induced ventricular arrhythmias- (2015)
  • Author(s): Ueoka A, Morita H, Kubo M, Nakagawa K, Nishii N, Nagase S, Ito H.
  • Organizer: 第30回日本不整脈学会学術大会・第32回日本心電学会学術集会 合同学術大会
  • Place of Presentation: 国立京都国際会議場（京都府京都市）
  • Year and Date: 2015-07-29
• [Presentation] Biological pacemaker created by HCN4-overexpressing mouse embryonic stem cell-derived cardiomyocyte. (2015)
  • Author(s): Nakamura K, Saito Y, Sugiyama H, Morita H, Ito H.
  • Organizer: 第30回日本不整脈学会学術大会・第32回日本心電学会学術集会 合同学術大会
  • Place of Presentation: 国立京都国際会議場（京都府京都市）
  • Year and Date: 2015-07-28
• [Presentation] The impact of evaluation of the sympathetic activity by abrupt starting exercise protocol in patients with congenital long QT syndrome. (2015)
  • Author(s): Tachibana M, Sugiyama H, Morita H, Nishii N, Nakamura K, Nagase S, Ohe T, Ito H.
  • Organizer: 第30回日本不整脈学会学術大会・第32回日本心電学会学術集会 合同学術大会
  • Place of Presentation: 国立京都国際会議場（京都府京都市）
  • Year and Date: 2015-07-28
• [Presentation] The impact of characteristic ECG morphology on the occurrence of ventricular fibrillation in hypothermic patients with Osborn wave. (2015)
  • Author(s): Sugiyama H, Morita H, Tachibana M, Nakagawa K, Nishii N, Nakamura K, Nagase S, Ito H.
  • Organizer: 第30回日本不整脈学会学術大会・第32回日本心電学会学術集会 合同学術大会
  • Place of Presentation: 国立京都国際会議場（京都府京都市）
  • Year and Date: 2015-07-28
• [Presentation] The impact of the drastic evaluation of the sympathetic activity by abrupt starting exercise protocol in patients with congenital long QT syndrome. (2015)
  • Author(s): Tachibana M, Sugiyama H, Nishii N, Nakamura K, Nagase S, Ohe T, Ito H, Morita H.
  • Organizer: Heart Rhythm 2015
  • Place of Presentation: Boston Convention & Exhibition Center(ボストン、アメリカ合衆国）
  • Year and Date: 2015-05-13
  • Int'l Joint Research
• [Presentation] Diagnostic and prognostic value of fever-induced Brugada syndrome. (2015)
  • Author(s): Mizusawa Y, Morita H, Adler A, Havakuk O, Thollet A, Maury JP, Wang DW, Hong K, Gandjbakhch F, Sacher F, Amin A, Lahrouchi N, Tan HL, Antzlevitch C, Probst V, Viskin S, Wilde A.
  • Organizer: Heart Rhythm 2015
  • Place of Presentation: Boston Convention & Exhibition Center(ボストン、アメリカ合衆国）
  • Year and Date: 2015-05-13
  • Int'l Joint Research
• [Presentation] Analysis of endocardial unipolar and bipolar electrograms in non-ischemic and ischemic cardiomyopathy patients with ventricular tachycardia. (2015)
  • Author(s): Nagase S, Nakagawa K, Kubo M, Ueoka A, Tachibana M, Miyoshi A, Nishii N, Morita H, Nakamura K, Ito H.
  • Organizer: Heart Rhythm 2015
  • Place of Presentation: Boston Convention & Exhibition Center(ボストン、アメリカ合衆国）
  • Year and Date: 2015-05-13
  • Int'l Joint Research
• [Presentation] Significance of the fragmented endocardial potential recorded by unipolar electrode on the lethal arrhythmic events in patients with Brugada syndrome. (2015)
  • Author(s): Ueoka A, Nagase S, Morita H, Kubo M, Nakagawa K, Nishii N, Ito H.
  • Organizer: Heart Rhythm 2015
  • Place of Presentation: Boston Convention & Exhibition Center(ボストン、アメリカ合衆国）
  • Year and Date: 2015-05-13
  • Int'l Joint Research
• [Presentation] Unexpected QRS widening with T wave alternans in patients with Brugada syndrome and SCN5A mutation. (2015)
  • Author(s): Ueoka A, Morita H, Kubo M, Nakagawa K, Nishii N, Nagase S, Ito H.
  • Organizer: Heart Rhythm 2015
  • Place of Presentation: Boston Convention & Exhibition Center(ボストン、アメリカ合衆国）
  • Year and Date: 2015-05-13
  • Int'l Joint Research
• [Presentation] Which antiarrhythmic drugs should be used as the first-line therapy for reducing recurrent ventricular fibrillation episodes in patients with Brugada syndrome? (2015)
  • Author(s): Morita H, Nagase S, Nishii N, Tachibana M, Ueoka A, Miyoshi A, Kubo M, Ito H.
  • Organizer: Heart Rhythm 2015
  • Place of Presentation: Boston Convention & Exhibition Center(ボストン、アメリカ合衆国）
  • Year and Date: 2015-05-13
  • Int'l Joint Research
• [Presentation] The significance of positron emission tomography to detect the underlying inflammatory cardiomyopathy with arrhythmogenicity. (2015)
  • Author(s): Tachibana M, Nagase S, Ueoka A, Miyoshi A, Takaya Y, Kubo M, Nakagawa K, Nishii N, Nakamura K, Morita H, Ito H.
  • Organizer: Heart Rhythm 2015
  • Place of Presentation: Boston Convention & Exhibition Center(ボストン、アメリカ合衆国）
  • Year and Date: 2015-05-13
  • Int'l Joint Research
• [Presentation] Prognostic value of early repolarization pattern in development of VT/VF following MI, hypothermia etc. (2015)
  • Author(s): Morita H.
  • Organizer: J wave Consensus Conference Agenda
  • Place of Presentation: Riverside Hotel Shanghai(中国、上海）
  • Year and Date: 2015-04-21
  • Int'l Joint Research / Invited
• [Book] Early Repolarization Syndrome (2017)
  • Author(s): Watanabe A, Morita H.
  • Total Pages: 107
  • Publisher: Springer
  • ISBN: 9789811033797
• [Book] J Wave Syndromes. Brugada and Early Repolarization Syndromes. (2016)
  • Author(s): Morita H, Sugiyama H.
  • Total Pages: 327
  • Publisher: Springer
• [Book] 右心不全を識り、評価して治療に生かす (2016)
  • Author(s): 森田 宏.
  • Total Pages: 169
  • Publisher: 文光堂
• [Book] 不整脈2015 (2015)
  • Author(s): 橘元見、森田 宏
  • Total Pages: 216
  • Publisher: メディカルレビュー社