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Development of intravascular ultrasound for the evaluation of coronary stress

Research Project

Project/Area Number 15K09119
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Cardiovascular medicine
Research InstitutionGifu University

Principal Investigator

Kawasaki Masanori  岐阜大学, 医学部附属病院, 准教授 (50214630)

Research Collaborator TANAKA Shinichiro  
YAGAMI Hiroyuki  
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords血管内超音波 / 力学的ストレス / 冠動脈 / 動脈硬化 / 血管内 / スペックル・トラッキング・エコー技術 / 動脈硬化危険因子
Outline of Final Research Achievements

Recently, two-dimensional speckle tracking echocardiography has been used to evaluate heart function. We applied this technique that is used for the evaluation of heart function to coronary arteries. The velocity vectors in the two-dimensional plane are displayed throughout the cardiac cycle, representing displacement of the speckles in relation to each other along the internal contour of coronary artery. Using this system, time-area curve can be automatically and promptly provided. We named this technique speckle tracking intravascular ultrasound (ST-IVUS). We determined the feasibility of evaluating strain and area of coronary plaque using ST-IVUS. There were strong correlation between luminal area by manual measurement and that by ST-IVUS measurement at both end-systole (r =0.98, p < 0.001) and end-diastole (r =0.98, p < 0.001). The strains of coronary arteries in the patients with diabetes mellitus.correlated with the level of HbA1c.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (11 results)

All 2018 2017 2016

All Presentation (11 results) (of which Int'l Joint Research: 1 results,  Invited: 2 results)

  • [Presentation] IB-IVUSの60MHz-IVUSへの応用と力学的ストレス解析のためのスペックルトラッキングIVUS (ST-IVUS)の開発2018

    • Author(s)
      川崎雅規
    • Organizer
      第28回日本心血管画像動態学会 (シンポジウム)
    • Related Report
      2017 Annual Research Report
  • [Presentation] Different Features of Coronary Plaques in Patients with Diabetes Mellitus Comparing with Dyslipidemia: A Speckle-tracking Intravascular Ultrasound Study2018

    • Author(s)
      川崎雅規、田中新一郎、野田俊之、湊口信也
    • Organizer
      第82回日本循環器学会 (シンポジウム)
    • Related Report
      2017 Annual Research Report
  • [Presentation] Property of Coronary Plaque: Evaluated by Speckle-tracking Intravascular Ultrasound (ST-IVUS)2018

    • Author(s)
      田中新一郎、川崎雅規、野田俊之、久保田知希、岩間眞、瀬川知則、西垣和彦、渡辺佐知郎、皆川太郎、湊口信也
    • Organizer
      第82回日本循環器学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Mechanical Properties of Coronary Plaques -Comparison with Integrated Backscatter Intravascular Ultrasound (IVUS) and Speckle-tracking IVUS-2018

    • Author(s)
      田中新一郎、川崎雅規、野田俊之、久保田知希、岩間眞、瀬川知則、西垣和彦、渡辺佐知郎2、皆川太郎、湊口信也
    • Organizer
      第82回日本循環器学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Mechanical Stress in Coronary Plaques Evaluated by Speckle Tracking Intravascular Ultrasound2017

    • Author(s)
      川崎雅規
    • Organizer
      Korea Cardiovascular Intervention Imaging Forum 2017
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] IB-IVUSとスペックルトラッキングIVUS (ST-IVUS)によるvulnerable plaqueの診断2017

    • Author(s)
      川崎雅規
    • Organizer
      第31回日本心臓血管内視鏡学会 (シンポジウム)
    • Related Report
      2017 Annual Research Report
  • [Presentation] 冠動脈プラークの組織性状と物理的ストレスの関連:Integrated Backscatter IVUSとSpeckle-tracking IVUSでの検討2017

    • Author(s)
      田中新一郎、川崎雅規、野田俊之、瀬川知則、西垣和彦、渡邉佐知郎、皆川太郎、湊口信也
    • Organizer
      第65回日本心臓病学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 60MHz血管内超音波(IVUS)IB-IVUSの開発とスペックルトラッキングIVUS (ST-IVUS)による冠動脈不安定プラークの検出2017

    • Author(s)
      川崎雅規
    • Organizer
      第65回日本心臓病学会 (シンポジウム)
    • Related Report
      2017 Annual Research Report
  • [Presentation] スペックルトラッキング血管内超音波(ST-IVUS)の開発とIB-IVUSとの組み合わせによる冠動脈不安定プラークの検出2016

    • Author(s)
      川崎雅規
    • Organizer
      日本心臓病学会
    • Place of Presentation
      東京
    • Year and Date
      2016-09-24
    • Related Report
      2015 Research-status Report
  • [Presentation] スペックル・トラッキング血管内超音波の開発とIB-IVUSとの組み合わせによる冠動脈不安定プラークの検出2016

    • Author(s)
      川崎雅規
    • Organizer
      日本心臓病学会
    • Place of Presentation
      東京
    • Related Report
      2016 Research-status Report
  • [Presentation] Evaluation of Coronary Plaque Stress by Speckle Tracking Intravascular Ultrasound2016

    • Author(s)
      川崎雅規
    • Organizer
      Korea Cardiovascular Intervention Imaging Forum 2016
    • Place of Presentation
      ソウル(韓国)
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited

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Published: 2015-04-16   Modified: 2019-03-29  

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