Impact of comprehensive rehabilitationon coronary plaque volume and components in coronary artery disease patients
Project/Area Number |
15K09128
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Cardiovascular medicine
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Research Institution | Juntendo University |
Principal Investigator |
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Co-Investigator(Renkei-kenkyūsha) |
SHIMADA KAZUNORI 順天堂大学, 医学部, 先任准教授 (60327814)
FUJIMOTO SHINICHIROU 順天堂大学, 医学部, 准教授 (70385871)
YOKOYAMA MIHO 順天堂大学, 医学部, 助教 (60407301)
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Project Period (FY) |
2015-04-01 – 2018-03-31
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Project Status |
Completed (Fiscal Year 2017)
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Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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Keywords | 急性冠症候群 / 320列冠動脈CT / 冠動脈プラーク / 包括的心臓リハビリテーション / 身体活動量 / 320列冠動脈CT / 320列冠動脈CT |
Outline of Final Research Achievements |
This study is a prospective study that examined quantity and qualitative alteration of the atherosclerotic plaque using the coronary computed tomography angiography (CCTA) in patients with coronary artery disease (CAD) participating cardiac rehabilitation. We enrolled 12 CAD patients (10 men, average age 64±9 years old) who underwent CCTA between December, 2017 and August, 2016. We recommended to have aerobic exercise of 3.6 METs based on the result of cardiopulmonary exercise test, and their physical activity was 9633±3847 steps/day. After 1 year, in one case (the target vessel was left anterior descending artery) that was available for plaque analysis, the plaque volume and lipid component volume were reduced using Labeling method. Cardiac rehabilitation may retard coronary plaque progression and reduce lipid component in CAD patients. The evaluation of the quality of the plaque was possible using CCTA.
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Report
(4 results)
Research Products
(41 results)
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[Journal Article] Clinical Characteristics and Long-Term Outcomes of Rotational Atherectomy - J2T Multicenter Registry2018
Author(s)
Okai I, Dohi T, Okazaki S, Jujo K, Nakashima M, Otsuki H, Tanaka K, Arashi H, Okabe R, Nagura F, Nara Y, Tamura H, Kurata T, Kawashima H, Kyono H, Yamaguchi J, Miyauchi K, Kozuma K, Hagiwara N, Daida H
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Journal Title
Circ J.
Volume: 82
Pages: 369-375
NAID
Related Report
Peer Reviewed / Open Access
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[Journal Article] Preprocedural High-Sensitivity C-Reactive Protein Predicts Long-Term Outcome of Percutaneous Coronary Intervention.2017
Author(s)
Wada H, Dohi T, Miyauchi K, Shitara J, Endo H, Doi S, Naito R, Konishi H, Tsuboi S, Ogita M, Kasai T, Hassan A, Okazaki S, Isoda K, Shimada K, Suwa S, Daida H.
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Journal Title
Circ J.
Volume: 81
Pages: 90-95
NAID
Related Report
Peer Reviewed / Open Access
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[Journal Article] Incremental prognostic value of coronary computed tomographic angiography high-risk plaque characteristics in newly symptomatic patients.2016
Author(s)
Fujimoto S, Kondo T, Takamura K, Baber U, Shinozaki T, Nishizaki Y, Kawaguchi Y, Matsumori R, Hiki M, Miyauchi K, Daida H, Hecht H, Stone GW, Narula J.
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Journal Title
J Cardiol.
Volume: 67
Pages: 538-44
Related Report
Peer Reviewed
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[Journal Article] Prognostic Value of Coronary Computed Tomography (CT) Angiography and Coronary Artery Calcium Score Performed Before Revascularization.2015
Author(s)
Fujimoto S, Kondo T, Kumamaru KK, Shinozaki T, Takamura K, Kawaguchi Y, Matsumori R, Hiki M, Miyauchi K, Daida H, Rybicki FJ.
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Journal Title
J Am Heart Assoc.
Volume: 4
Related Report
Peer Reviewed / Open Access
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[Journal Article] Effects of Phase II Comprehensive Cardiac Rehabilitation on Coronary Plaque Volume After Acute Coronary Syndrome.2015
Author(s)
Nishitani-Yokoyama M, Miyauchi K, Shimada K, Miyazaki T, Ogita M, Okazaki S, Shioya M, Koba S, Tsujita H, Kobayashi Y, Daida H.
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Journal Title
Int Heart J.
Volume: 56
Pages: 597-604
NAID
Related Report
Peer Reviewed / Open Access
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[Journal Article] Incremental prognostic value of coronary computed tomographic angiography high-risk plaque characteristics in newly symptomatic patients.2015
Author(s)
Fujimoto S, Kondo T, Takamura K, Baber U, Shinozaki T, Nishizaki Y, Kawaguchi Y, Matsumori R, Hiki M, Miyauchi K, Daida H, Hecht H, Stone GW, Narula J.
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Journal Title
J Cardiol.
Volume: 15
Pages: 241-5
Related Report
Peer Reviewed
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[Presentation] The Predictive Factors Affecting Diagnostic Accuracy in On-Site Operated Novel CT-Fractional Flow Reserve Based on Fluid and Structural Interaction.2017
Author(s)
Kawaguchi Y, Fujimoto S, Kawasaki T, Kumamaru KK, Dohi T, Kato E, Aoshima C, Takamura K, Kato Y, Hiki M, Okazaki S, Rybicki FJ, Daida H.
Organizer
90th Scientific Session AHA
Related Report
Int'l Joint Research
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[Presentation] The Predictive Factors Affecting Diagnostic Performance on Novel CT-Fractional Flow Reserve Based on Fluid Structual Interaction.2017
Author(s)
Kawaguchi Y, Fujimoto S, Kumamaru K, Dohi T, Ri K, Yamada S, Takamura K, Kato E, Hiki M, Kato Y, Okazaki S, Daida H.
Organizer
SCCT 2017 12th Annual Scientific meeting
Related Report
Int'l Joint Research
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[Presentation] Incremental prognostic value of coronary computed tomographic angiography high risk plaque characteristics in asymptomatic patients.2016
Author(s)
Takamura K, Fujimoto S, Kondo T, Hiki M, Matsumori R, Kawaguchi Y, Suda S, Kato E, Kumamaru K, Takase S, Daida H.
Organizer
The American College of Cardiology 65nd Annual Scientific Session
Place of Presentation
USA,シカゴ
Year and Date
2016-04-02
Related Report
Int'l Joint Research
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[Presentation] Retrospective Evaluation of CT Angiography Transluminal Attenuation Gradient for the Detection of Compromised Fractional Flow Reserve.2016
Author(s)
Etsuro Kato, Shinichiro Fujimoto, Yuko Kawaguchi, Rie Matsumori, Kazuhisa Takamura, Katsumi Miyauchi, Sweatkar Rani, Agarwal Mukta, Giannopoulos Andreas, Kanako Kumamaru, Rybicki Frank, Hiroyuki Daida
Organizer
第80回日本循環器学会学術集会
Place of Presentation
仙台
Year and Date
2016-03-18
Related Report
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[Presentation] Prognostic Value of Coronary CT Angiography and Coronary Artery Calcium Score Performed Before Revascularization.2015
Author(s)
Takamura: K, Fujimoto S, Kondo T, Kumamaru K, Kawaguchi Y, Suda S, Matsumori R., Kato E, Hiki M, Takase S, Rybicki FJ, Daida H.
Organizer
American Heart Association, 88th Scientific Session
Place of Presentation
Orland (USA)
Year and Date
2015-11-07
Related Report
Int'l Joint Research
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