Essential roles of ghrelin in cancer biology

Research Project

Project/Area Number	15K09178
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Research Field	Respiratory organ internal medicine
Research Institution	University of Miyazaki
Principal Investigator	IIBOSHI HIROTOSHI 宮崎大学, 医学部, 助教 (80631473)
Co-Investigator(Kenkyū-buntansha)	松元信弘宮崎大学, 医学部, 助教 (70418838)
Project Period (FY)	2015-04-01 – 2018-03-31
Project Status	Completed (Fiscal Year 2017)
Budget Amount *help	¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000) Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000) Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000) Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords	肺癌 / グレリン / 抗癌剤 / 化学療法 / 摂食
Outline of Final Research Achievements	In advanced lung cancer patients, who received anti-cancer chemotherapy including platinum-based regimen, the serum levels of ghrelin were measured. The serum levels of acyl-ghrelin decreased with administration of the drugs and recovered within a week. The appetite and food intake was correlated with the serum levels of acyl-ghrelin.

Report

(4 results)