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Establishment of the pervasive evaluation system of physical activity in COPD

Research Project

Project/Area Number 15K09187
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Respiratory organ internal medicine
Research InstitutionWakayama Medical University

Principal Investigator

Minakata Yoshiaki  和歌山県立医科大学, 医学部, 博士研究員 (80295815)

Co-Investigator(Kenkyū-buntansha) 早田 敦志  和歌山県立医科大学, 医学部, 助教 (20458061)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords身体活動性 / COPD / 加速度計 / 維持・向上 / 3軸加速度計 / 歩行速度 / 呼吸困難 / 3軸加速度計 / 医療介入 / 気管支拡張薬 / 再現性
Outline of Final Research Achievements

We evaluated the validity of a triaxial accelerometer, Active Style Pro HJA-750C; (HJA). The values of physical activity (PA) measured by HJA were significantly correlated with those by 2 already validated accelerometers, and the validity of HJA was confirmed. The PA on rainy day was suppressed but that on holiday was not. Analysis with at least 3 days was required for repeatability. In COPD patients, the walking time, walking distance and total step count were lower but the walking velocity was not different compared to healthy subjects. The mMRC>=2 could predict the condition of physical inactivity. Additional administration of bronchodilator enhanced PA at >=3.0 and >=3.5METs, and the enhancement was greater in patients with better pulmonary function. An improvement in PA at >=2.0METs was seen with the combination drug of 2 bronchodilators compared to the single agent.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (29 results)

All 2018 2017 2016 2015

All Journal Article (19 results) (of which Int'l Joint Research: 7 results,  Open Access: 6 results,  Peer Reviewed: 7 results,  Acknowledgement Compliant: 3 results) Presentation (10 results) (of which Invited: 5 results)

  • [Journal Article] COPD患者の身体活動性の科学的分析を目指して2018

    • Author(s)
      南方良章
    • Journal Title

      アレルギーの臨床

      Volume: 38 Pages: 57-60

    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Journal Article] Breathing so you can move and moving so you can breathe2017

    • Author(s)
      Minakata Yoshiaki
    • Journal Title

      Scientia

      Volume: 111 Pages: 63-66

    • Related Report
      2017 Annual Research Report
    • Open Access / Int'l Joint Research
  • [Journal Article] Improved quality of life in asthma patients under long-term therapy: Assessed by AHQ-Japan2017

    • Author(s)
      Tohda Yuji、Iwanaga Takashi、Sano Hiroyuki、Kume Hiroaki、Hirata Kazuto、Ohkura Noriyuki、Tachibana Isao、Nishimura Yoshihiro、Matsumoto Hisako、Minakata Yoshiaki、Yoshikawa Masanori、Fujimura Masaki、the Kansai & Hokuriku Academy for Asthma Treatment
    • Journal Title

      Int J Clin Pract

      Volume: 71 Issue: 1 Pages: e12898-e12898

    • DOI

      10.1111/ijcp.12898

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Study Design of VESUTO?: Efficacy of Tiotropium/Olodaterol on Lung Hyperinflation, Exercise Capacity, and Physical Activity in Japanese Patients with Chronic Obstructive Pulmonary Disease2017

    • Author(s)
      Ichinose Masakazu、Minakata Yoshiaki、Motegi Takashi、Ueki Jun、Seki Tetsuo、Anzai Tatsuhiko、Takizawa Ayako、Gronke Lars、Hirata Kazuto
    • Journal Title

      Adv Ther.

      Volume: 34 Issue: 7 Pages: 1622-1635

    • DOI

      10.1007/s12325-017-0554-3

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 呼吸器疾患(COPD)と骨粗鬆症 COPDの身体活動性低下と治療介入による効果2017

    • Author(s)
      南方良章
    • Journal Title

      日本骨訴訟学会雑誌

      Volume: 3 Pages: 64-65

    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Journal Article] 呼吸リハビリテーションの評価 呼吸困難やADLと身体活動性の評価2017

    • Author(s)
      南方良章
    • Journal Title

      総合リハビリテーション

      Volume: 45 Pages: 1622-1635

    • NAID

      40021156213

    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Journal Article] COPD患者における身体活動性の重要性と向上・維持2017

    • Author(s)
      南方良章
    • Journal Title

      医療

      Volume: 71 Pages: 159-166

    • NAID

      40021193960

    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Journal Article] COPDと身体活動性2017

    • Author(s)
      南方良章
    • Journal Title

      COPD Total Management

      Volume: 5 Pages: 6-6

    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Journal Article] 肺と骨:呼吸器疾患(COPD)と骨粗鬆症.COPDの身体活動性低下と治療介入による効果2017

    • Author(s)
      南方良章
    • Journal Title

      日本骨訴訟学会雑誌

      Volume: 3 Pages: 64-65

    • Related Report
      2016 Research-status Report
  • [Journal Article] Walking Pattern in COPD Patients.2016

    • Author(s)
      Sakamoto Y, Sakamoto K, Minakata Y, Shiba S, Takeshi Nakamura T, Ichinose M, Tajima F.
    • Journal Title

      Rehabili Nurs

      Volume: 41 Issue: 4 Pages: 211-217

    • DOI

      10.1002/rnj.209

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Differences in physical activity according to mMRC grade in patients with COPD2016

    • Author(s)
      Hayata A, Minakata Y, Matsunaga K, Nakanishi M, Yamamoto N
    • Journal Title

      Int J Chron Obstruct Pulmon Dis

      Volume: 11 Pages: 2203-2208

    • DOI

      10.2147/copd.s109694

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] COPDの身体活動性研究 up-to-date2016

    • Author(s)
      南方良章
    • Journal Title

      日本呼吸ケア・リハビリテーション学会誌

      Volume: 26 Pages: 33-38

    • NAID

      130005148003

    • Related Report
      2016 Research-status Report
  • [Journal Article] 呼吸器疾患診療の最新情報 トピックスⅡ. COPD; 2. 身体活動性の重要性とその向上法2016

    • Author(s)
      南方良章
    • Journal Title

      日本内科学会雑誌

      Volume: 105 Pages: 963-969

    • Related Report
      2016 Research-status Report
  • [Journal Article] Effects of pharmacologic treatment based on airflow limitation and breathlessness on daily physical activity in patients with chronic obstructive pulmonary disease2015

    • Author(s)
      Minakata Y, Morishita Y, Ichikawa T, Akamatsu K, Hirano T, Nakanishi M, Matsunaga K, Ichinose M
    • Journal Title

      Int J Chron Obstruct Pulmon Dis

      Volume: 10 Pages: 1275-1282

    • DOI

      10.2147/copd.s84134

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Cigarette smoke augments MUC5AC production via the TLR3-EGFR pathway in airway epithelial cells.2015

    • Author(s)
      K. Kanai, A. Koarai, Y.Shishikura, H. Sugiura, T. Ichikawa, T. Kikuchi, K. Akamatsu, T. Hirano, M. Nakanishi, K. Matsunaga, Y. Minakata and M.Ichinose.
    • Journal Title

      Respir Investig.

      Volume: in press Issue: 4 Pages: 137-148

    • DOI

      10.1016/j.resinv.2015.01.007

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Progression of Irreversible Airflow Limitation in Asthma: Correlation with Severe Exacerbations2015

    • Author(s)
      Matsunaga K, Hirano T, Oka A, Tanaka A, Kanai K, Kikuchi T, Hayata A, Akamatsu H, Akamatsu K, Koh Y, Nakanishi M, Minakata Y, Yamamoto N
    • Journal Title

      J Allergy Clin Immunol Pract

      Volume: 3 Issue: 5 Pages: 759-764

    • DOI

      10.1016/j.jaip.2015.05.005

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] COPDの身体活動性をめぐるサイエンス 身体活動性の評価法2015

    • Author(s)
      南方良章
    • Journal Title

      日本呼吸器学会雑誌

      Volume: 4 Pages: 8-14

    • Related Report
      2015 Research-status Report
  • [Journal Article] COPD病態理解の変遷と治療の新展開 COPDによる身体活動性低下2015

    • Author(s)
      南方良章
    • Journal Title

      Progress in Medicine

      Volume: 35 Pages: 219-222

    • Related Report
      2015 Research-status Report
  • [Journal Article] COPD患者の身体活動性評価と改善に向けた取り組み2015

    • Author(s)
      南方良章
    • Journal Title

      日本呼吸ケア・リハビリテーション学会誌

      Volume: 25 Pages: 77-81

    • NAID

      130005098552

    • Related Report
      2015 Research-status Report
  • [Presentation] COPD治療のUp-Date 増悪に対する治療戦略2017

    • Author(s)
      南方良章
    • Organizer
      第57回日本呼吸器学会学術講演会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 日本人COPD患者の身体活動性測定法の共有化と標準式作成(SPACE試験)H29年中間登録状況2017

    • Author(s)
      南方良章、駿田直俊、東祐一郎
    • Organizer
      第71回国立病院総合医学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 気管支拡張薬によるCOPD患者の身体活動性改善効果の検討2016

    • Author(s)
      南方良章
    • Organizer
      第42回吸入療法研究会
    • Place of Presentation
      東京
    • Year and Date
      2016-02-13
    • Related Report
      2015 Research-status Report
  • [Presentation] 呼吸ケア・リハビリテーション学会共同企画 慢性呼吸器疾患における身体活動性を考える 3. 身体活動性の計測と向上への取り組み2016

    • Author(s)
      南方良章
    • Organizer
      第56回日本呼吸器学会学術講演会
    • Place of Presentation
      京都
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] COPDトータルマネージメント~COPD治療の最新情報~.身体活動性に対する影響2016

    • Author(s)
      南方良章
    • Organizer
      第56回日本呼吸器学会学術講演会 ランチョンセミナー
    • Place of Presentation
      京都
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] COPD身体活動性評価のための普及型機種確立を目指した新規3軸加速度計の妥当性検証2016

    • Author(s)
      南方良章
    • Organizer
      第56回日本呼吸器学会学術講演会
    • Place of Presentation
      京都
    • Related Report
      2016 Research-status Report
  • [Presentation] シンポジウム肺と骨:呼吸器疾患(COPD)と骨粗鬆症.COPDの身体活動性低下と治療介入による効果2016

    • Author(s)
      南方良章
    • Organizer
      第18回日本骨粗鬆症学会
    • Place of Presentation
      仙台
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] 日本人COPD患者の身体活動性測定法の共有化と標準式作成(SPACE試験)2016

    • Author(s)
      南方良章
    • Organizer
      第70回国立病院総合医学会
    • Place of Presentation
      沖縄
    • Related Report
      2016 Research-status Report
  • [Presentation] 3軸加速度計Active style Pro HJA-750Cの妥当性検証2015

    • Author(s)
      宮本勢子、河野明、駿田直俊、南方良章
    • Organizer
      第25回日本呼吸ケア・リハビリテーション学会学術集会
    • Place of Presentation
      千葉
    • Year and Date
      2015-10-15
    • Related Report
      2015 Research-status Report
  • [Presentation] COPDの身体活動性研究up-to-date2015

    • Author(s)
      南方良章
    • Organizer
      第25回日本呼吸ケア・リハビリテーション学会学術集会
    • Place of Presentation
      千葉
    • Year and Date
      2015-10-15
    • Related Report
      2015 Research-status Report
    • Invited

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Published: 2015-04-16   Modified: 2019-03-29  

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