| Project/Area Number |
15K09361
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Neurology
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| Research Institution | Teikyo University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
HATANAKA Yuki 帝京大学, 医学部, 講師 (40322458)
OGAWA Go 帝京大学, 医学部, 助教 (50632311)
HOKKOKU Keiichi 帝京大学, 医学部, 助教 (80623355)
MIYAJI Yosuke 帝京大学, 医学部, 助教 (30734959)
KANBAYASHI Takamichi 帝京大学, 医学部, 臨床助手 (00774423)
HIGASHIHARA Mana 東京都健康長寿医療センター, 医長 (20622476)
OISHI Chizuko 杏林大学, 医学部, 助教 (50406980)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 表面筋電図 / 針筋電図 / 定量解析 / 神経原性変化 / 筋原性変化 / Clustering Index法 |
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| Outline of Final Research Achievements |
We conducted following studies as the clinical application of the Clustering Index method, a non-invasive analysis method of surface EMG. 1) We obtained data at the tibialis anterior muscle from 29 neurogenic and 39 myopathic subjects and determined the appropriate window width. The sensitivity of 97% in neurogenic and 72% in myopathic subjects was achieved using this window width. 2) We applied CI method to children and tried to differentiate 16 neurogenic and 29 myopathic children. Certain utility was documented although the sensitivity was not so good as in adults. 3) We investigated new parameters, Size Index and revised Size Index, in quantitative analysis of the motor unit potential in needle EMG. 4) We compared the sensitivity between CI method and needle EMG. 5) We conducted other related investigations regarding various disorders in which CI method may be applicable, such as carpal tunnel syndrome, amyotrophic lateral sclerosis, or Guillan-Barre syndrome.
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