Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
Outline of Final Research Achievements |
Peripheral nerve ageing has been studied in large myelinated nerve fibers. However, ageing of small myelinated and unmyelinated nerve fibers are unknown. We have found a loss of small nerve fibres in subjects over 85 y.o. using the new techniques of skin biopsy. We have also observed severe nerve atrophy of large nerve fibres in the accerelated ageing mouse model. These results suggested that small nerve fibres are affectd by ageing as well as large nerve fibres. As the super-aging society approaches, the understanding of ageing including the peripheral nervous system, is a societal need.
|